Golsteijn R H J, Bolman C, Volders E, Peels D A, de Vries H, Lechner L
Department of Psychology and Educational Sciences, Open University of the Netherlands, Heerlen, PO, Box 2960, 6401 DL Heerlen, The Netherlands.
Department of Health Promotion, Maastricht University, Maastricht, The Netherlands.
BMC Cancer. 2017 Jun 26;17(1):446. doi: 10.1186/s12885-017-3397-z.
Cancer and cancer treatment coincide with substantial negative physical, psychological and psychosocial problems. Physical activity (PA) can positively affect the negative effects of cancer and cancer treatment and thereby increase quality of life in CPS. Nevertheless, only a minority of CPS meet PA guidelines. We developed the OncoActive (OncoActief in Dutch) intervention: a computer-tailored PA program to stimulate PA in prostate and colorectal CPS, because to our knowledge there are only a few PA interventions for these specific cancer types in the Netherlands METHODS: The OncoActive intervention was developed through systematic adaptation of a proven effective, evidence-based, computer-tailored PA intervention for adults over fifty, called Active Plus. The Intervention Mapping (IM) protocol was used to guide the systematic adaptation. A literature study and interviews with prostate and colorectal CPS and health care professionals revealed that both general and cancer-specific PA determinants are important and should be addressed. Change objectives, theoretical methods and applications and the actual program content were adapted to address the specific needs, beliefs and cancer-related issues of prostate and colorectal CPS. Intervention participants received tailored PA advice three times, on internet and with printed materials, and a pedometer to set goals to improve PA. Pre- and pilot tests showed that the intervention was highly appreciated (target group) and regarded safe and feasible (healthcare professionals). The effectiveness of the intervention is being evaluated in a randomized controlled trial (RCT) (n = 428), consisting of an intervention group and a usual care waiting-list control group, with follow-up measurements at three, six and twelve months. Participants are recruited from seventeen hospitals and with posters, flyers and calls in several media.
Using the Intervention Mapping protocol resulted in a systematically adapted, theory and evidence-based intervention providing tailored PA advice to prostate and colorectal CPS. If the intervention turns out to be effective in increasing PA, as evaluated in a RCT, possibilities for nationwide implementation and extension to other cancer types will be explored.
The study is registered in the Dutch Trial Register (NTR4296) on November 23rd 2013 and can be accessed at http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4296 .
癌症及癌症治疗伴随着大量负面的身体、心理和社会心理问题。体育活动（PA）能够对癌症及癌症治疗的负面影响产生积极作用，从而提高癌症患者及幸存者（CPS）的生活质量。然而，只有少数癌症患者及幸存者达到了体育活动指南的要求。我们开发了“OncoActive”（荷兰语为“OncoActief”）干预措施：一种针对前列腺癌和结直肠癌患者及幸存者的计算机定制体育活动计划，旨在促进他们的体育活动，因为据我们所知，在荷兰针对这些特定癌症类型的体育活动干预措施很少。方法：“OncoActive”干预措施是通过对一种已被证明有效的、基于证据的、针对五十岁以上成年人的计算机定制体育活动干预措施“Active Plus”进行系统改编而开发的。采用干预映射（IM）协议来指导系统改编。一项文献研究以及对前列腺癌和结直肠癌患者及幸存者以及医疗保健专业人员的访谈表明，一般的和特定于癌症的体育活动决定因素都很重要，都应予以关注。对改变目标、理论方法和应用以及实际计划内容进行了调整，以满足前列腺癌和结直肠癌患者及幸存者的特定需求、信念和与癌症相关的问题。干预参与者通过互联网和印刷材料三次获得量身定制的体育活动建议，并获得一个计步器以设定目标来改善体育活动。预测试和试点测试表明，该干预措施受到高度赞赏（目标群体），并且被认为是安全可行的（医疗保健专业人员）。正在一项随机对照试验（RCT）（n = 428）中评估该干预措施的有效性，该试验包括一个干预组和一个常规护理等待名单对照组，并在三个月、六个月和十二个月进行随访测量。参与者从十七家医院招募，并通过海报、传单以及在多家媒体上发布的广告进行招募。
使用干预映射协议产生了一种系统改编的、基于理论和证据的干预措施，为前列腺癌和结直肠癌患者及幸存者提供量身定制的体育活动建议。如果在随机对照试验中评估该干预措施在增加体育活动方面被证明是有效的，将探索在全国范围内实施并扩展到其他癌症类型的可能性。
该研究于2013年11月23日在荷兰试验注册中心（NTR4296）注册，可在http://www.trialregister.nl/trialreg/admin/rctview.asp?TC=4296上查阅。
