Dubois C, Liegeon A-L, Fabbro C, Truchetet F
Service de dermatologie, CHR Metz Thionville, 1-3, rue du Friscaty, 57100 Thionville, France.
Service de dermatologie, CHR Metz Thionville, 1-3, rue du Friscaty, 57100 Thionville, France.
Ann Dermatol Venereol. 2017 Oct;144(10):621-623. doi: 10.1016/j.annder.2017.05.007. Epub 2017 Jun 23.
Neisseria meningitidis (NM) is a commensal bacteria present in the oropharyngeal flora that causes invasive infections. There have been rarer reports of presence in the genital region. Herein, we present two cases of acute NM urethritis.
Two men aged 30 and 31years, one of whom is homosexual and seropositive for HIV infection, presented urethral discharge which was diagnosed as acute urethritis. The unit through samples indicated the presence of NM of serogroups B and C. One of the antibiotic sensitivity tests revealed intermediate susceptibility to penicillin G and to amoxicillin.
The clinical presentation of acute NM urethritis is non-specific, because of which urethral samples should be taken wherever acute urethritis is suspected. NM urethritis is infrequent and primarily affects men who have sex with men (MSM). Its current increase is due to unprotected oral-genital sexual practices. Due to the emergence of resistance to NM, antibiotic susceptibility testing should be carried out routinely to ensure appropriate therapy and prophylaxis. Cases of invasive serogroup C meningococcal infections have been recorded within the MSM population with hypothetical sexual port of entry. Thus, the French High Public Health Authority recommends vaccination against meningitis C in this population.
脑膜炎奈瑟菌(NM)是一种存在于口咽菌群中的共生细菌,可引发侵袭性感染。关于其存在于生殖器区域的报道较为罕见。在此,我们报告两例急性NM尿道炎病例。
两名年龄分别为30岁和31岁的男性,其中一名为同性恋且HIV感染血清学阳性,出现尿道分泌物,被诊断为急性尿道炎。通过样本检测发现存在B群和C群NM。其中一项抗生素敏感性试验显示对青霉素G和阿莫西林中度敏感。
急性NM尿道炎的临床表现不具特异性,因此,凡怀疑有急性尿道炎,均应采集尿道样本。NM尿道炎较为罕见,主要影响男男性行为者(MSM)。其发病率目前上升是由于无保护的口交性行为。由于对NM出现耐药性,应常规进行抗生素敏感性试验,以确保适当的治疗和预防。在MSM人群中已记录到侵袭性C群脑膜炎球菌感染病例,推测有性传播途径。因此,法国公共卫生高级管理局建议该人群接种C群脑膜炎疫苗。