Department of Urology, Medical Faculty, Istinye University, Istanbul, Turkey.
Department of Urology, Medical Park Hospital, Muratpaşa, Antalya, Turkey.
Int Urol Nephrol. 2019 Jun;51(6):901-907. doi: 10.1007/s11255-019-02140-2. Epub 2019 Apr 5.
Non-gonococcal urethritis (NGU) is the most common disease of the genital tract in men. Recent studies have recommended avoiding the empiric antibiotic administrations that constitute the classical treatment approach in NGU and to aim toward treatment of causative pathogens. However, the classification of NGU agents remains controversial. In addition, the relevance of the commensalism of Mycoplasma hominis, Ureaplasma urealyticum, Ureaplasma parvum, and Gardnerella vaginalis, which are among the opportunistic pathogens found in the urethral flora, has yet to be determined. Furthermore, there are certain pathogens on which sufficient studies have not been conducted, although they are known to be NGU pathogens, and their statuses should be updated. In this review, the classification of NGU pathogens is summarized in the light of the current literature.
非淋菌性尿道炎（NGU）是男性生殖道最常见的疾病。最近的研究建议避免经验性抗生素治疗，这是 NGU 的经典治疗方法，并针对致病病原体进行治疗。然而，NGU 病原体的分类仍然存在争议。此外，在尿道菌群中发现的机会性病原体，如人型支原体、解脲脲原体、微小脲原体和阴道加德纳菌的共生关系的相关性尚未确定。此外，还有一些病原体虽然已知是 NGU 的病原体，但尚未进行充分的研究，其地位需要更新。在这篇综述中，根据当前文献总结了 NGU 病原体的分类。
