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神经妥乐平治疗小儿硬膜外麻醉后脊髓损伤所致下肢疼痛取得成功。

Success with neurotropin in treating pediatric lower extremity pain induced by spinal cord injury after epidural anesthesia.

作者信息

Zhu Mengye, Zhou Fuqing, Li Lingchao, Yin Qin, Qiu Mizhen, Zhang Yong

机构信息

Department of Pain Clinic.

Department of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang.

出版信息

J Pain Res. 2017 Jun 6;10:1391-1394. doi: 10.2147/JPR.S135037. eCollection 2017.

Abstract

Spinal cord injury (SCI) complicated by epidural anesthesia, though rare, can result in neuropathic pain. However, the treatment for this kind of life-altering injury remains a challenge. A 7-year-old girl was referred with dyskinesia and severe pain in her right lower extremity due to an accidental SCI following lumbar puncture. After treatment with analgesics such as gabapentin, mecobalamin, and dexamethasone/methylprednisolone for 1 week, the myodynamia had improved, but progressive pain persisted. After treatment with neurotropin, a gradual decrease in visual analog scale score from 7 to 0 was observed. We herein first describe that neurotropin produced sustained relief of pain induced by SCI. This case suggests that neurotropin might be a promising drug in treating pediatric neuropathic pain caused by SCI.

摘要

脊髓损伤(SCI)并发硬膜外麻醉,虽较为罕见,但可导致神经性疼痛。然而,针对这种改变生活的损伤的治疗仍然是一项挑战。一名7岁女孩因腰椎穿刺意外导致脊髓损伤,出现右下肢运动障碍和剧痛而前来就诊。在用加巴喷丁、甲钴胺以及地塞米松/甲基强的松龙等镇痛药治疗1周后,肌力有所改善,但持续性疼痛仍在进展。在用神经妥乐平治疗后,视觉模拟评分从7分逐渐降至0分。我们在此首次描述神经妥乐平可使脊髓损伤所致疼痛得到持续缓解。该病例表明神经妥乐平可能是治疗小儿脊髓损伤所致神经性疼痛的一种有前景的药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0236/5476653/e20a4875acae/jpr-10-1391Fig1.jpg

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