Kowar M, Jacobs A H
Klinik für Geriatrie mit Neurologie und Tagesklinik, Johanniter-Krankenhaus Bonn, Johanniterstr. 3-5, 53113, Bonn, Deutschland.
Internist (Berl). 2018 Jan;59(1):97-101. doi: 10.1007/s00108-017-0270-8.
An 89-year-old woman with Alzheimer's dementia was admitted because of altered orientation, aggressiveness and inability to take care of herself at home. Her patient history indicated that 14 days ago the battery of the pacemaker had be renewed. During that time the patient suffered from psychomotor alterations. Therefore, melperone had been initiated. Inspection of the urine and laboratory findings pointed towards an acute exacerbation of acute intermittent porphyria as a possible cause of the delirium. After discontinuation of melperone with additional parenteral therapy with physiological fluids, the signs of delirium significantly improved.
一名89岁患有阿尔茨海默病痴呆症的女性因定向力改变、攻击性及在家中无法自理而入院。她的病史显示14天前起搏器的电池已更换。在此期间患者出现精神运动性改变。因此，开始使用甲哌氯丙嗪。尿液检查和实验室检查结果表明急性间歇性卟啉病急性加重可能是谵妄的原因。停用甲哌氯丙嗪并额外给予生理盐水肠外治疗后，谵妄症状明显改善。
