Ozturk Ayperi, Aktas Zafer, Yilmaz Aydin, Tari Pinar, Demirag Funda
Interventional Pulmonology Department, Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Ankara, Turkey.
Department of Nucleer Medicine, Atatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Ankara, Turkey.
Diagn Cytopathol. 2017 Dec;45(12):1122-1124. doi: 10.1002/dc.23775. Epub 2017 Jun 26.
Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) has an effective role in both diagnosis and management of patients with lung cancer. There are many reasons could cause false positivity on PET/CT.A 60-year-old man was admitted a mass on thorax CT and diagnosed as squamous cell carcinoma. Lobectomy with lymph node dissection was performed after evaluation of distant metastases. There were pathological lymph nodes detected on PET/CT at six month following period. Endobronchial ultrasonography guided transbronchial needle aspiration was performed for differantial diagnosis. The pathologic diagnosis was granuloma which developed in response to suture material. We interpreted this granulomatous reaction as gossypiboma which developed against long-left or forgotten suture material. In conclusion, based on this case, gossypiboma (or granulomatous inflammation in response to foreign bodies) should be also considered in differential diagnosis of intrathoracic lymph nodes with PET positivity in a previously operated patient.
氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG PET/CT）在肺癌患者的诊断和管理中都发挥着重要作用。PET/CT出现假阳性有多种原因。一名60岁男性因胸部CT发现肿块入院，被诊断为鳞状细胞癌。在评估远处转移后进行了肺叶切除加淋巴结清扫术。术后6个月PET/CT检查发现有病理淋巴结。为明确诊断，进行了支气管内超声引导下经支气管针吸活检。病理诊断为对缝合材料产生反应而形成的肉芽肿。我们将这种肉芽肿反应解释为针对遗留或遗忘的缝合材料形成的棉籽瘤。总之，基于此病例，对于既往接受过手术的患者，PET阳性的胸内淋巴结鉴别诊断中也应考虑棉籽瘤（或对外来物体产生的肉芽肿性炎症）。
