Puślecki Mateusz, Ligowski Marcin, Dąbrowski Marek, Sip Maciej, Stefaniak Sebastian, Kłosiewicz Tomasz, Gąsiorowski Łukasz, Karczewski Marek, Małkiewicz Tomasz, Ładzińska Małgorzata, Zieliński Marcin, Pawlak Aleksander, Perek Bartłomiej, Czekajlo Michael, Jemielity Marek
1 Poznan University of Medical Sciences, Department of Rescue and Disaster Medicine, Poznan, Poland.
2 Poznan University of Medical Sciences, Department of Cardiac Surgery and Transplantology; Clinical Hospital SKPP, Poznan, Poland.
Perfusion. 2017 Nov;32(8):624-630. doi: 10.1177/0267659117716533. Epub 2017 Jun 27.
Maintaining the viability of organs from donors after circulatory death (DCD) for transplantation is a complicated procedure, from a time perspective in the absence of appropriate organizational capabilities, that makes such transplantation cases difficult and not yet widespread in Poland. We present the procedural preparation for Poland's first case of organ (kidney) transplantation from a DCD donor in which perfusion was supported by extracorporeal membrane oxygenation (ECMO). Because this organizational model is complex and expensive, we used advanced high-fidelity medical simulation to prepare for the real-life implementation. The real time scenario included all crucial steps: prehospital identification, cardiopulmonary resuscitation (CPR), advanced life support (ALS); perfusion therapy (CPR-ECMO or DCD-ECMO); inclusion and exclusion criteria matching, suitability for automated chest compression; DCD confirmation and donor authorization, ECMO organs recovery; kidney harvesting. The success of our first simulated DCD-ECMO procedure in Poland is reassuring. Soon after this simulation, Maastricht category II DCD procedures were performed, involving real patients and resulting in two successful double kidney transplantations. During debriefing, it was found that the previous simulation-based training provided the experience to build a successful procedural chain, to eliminate errors at the stage of identification, notification, transportation, donor qualifications and ECMO organ perfusion to create DCD-ECMO algorithm architecture.
在循环性死亡(DCD)后维持供体器官用于移植的活力是一个复杂的过程,从时间角度来看,在缺乏适当组织能力的情况下,这使得此类移植病例在波兰既困难又尚未广泛开展。我们介绍了波兰首例来自DCD供体的器官(肾脏)移植的程序准备情况,其中灌注由体外膜肺氧合(ECMO)支持。由于这种组织模式复杂且昂贵,我们使用先进的高保真医学模拟来为实际实施做准备。实时场景包括所有关键步骤:院前识别、心肺复苏(CPR)、高级生命支持(ALS);灌注治疗(CPR-ECMO或DCD-ECMO);纳入和排除标准匹配、自动胸外按压的适用性;DCD确认和供体授权、ECMO器官获取;肾脏摘取。我们在波兰首次模拟的DCD-ECMO程序取得成功,令人安心。在这次模拟后不久,就进行了马斯特里赫特II类DCD程序,涉及真实患者,并成功进行了两次双肾移植。在汇报过程中发现,之前基于模拟的培训提供了构建成功程序链的经验,消除了识别、通知、运输、供体资格和ECMO器官灌注阶段的错误,从而创建了DCD-ECMO算法架构。