Cui Yanhui, Li Li, Wu Qian, Zhao Junyang, Chu Huihui, Yu Gang, Wei Wenbin
Department of Ophthalmology, Beijing Children's Hospital, National Center for Children's Health, China, Capital Medical University, National Key Discipline of Pediatrics, Ministry of Education; Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University .
Clin Invest Med. 2017 Jun 26;40(3):E117-E126. doi: 10.25011/cim.v40i3.28391.
The purpose of this study was to conduct a meta-analysis comparing rigid gas permeable lenses (RGP) with soft contact lenses (SCL), spectacles and orthokeratology (OK) lenses for myopia control with respect to axial length elongation, spherical equivalent and measures of corneal curvature.
Medline, Cochrane, EMBASE, and Google Scholar databases were searched to September 29, 2015 using the following keywords: rigid gas permeable contact lens; refractive error; and refractive abnormalities. Randomized controlled trials, two-arm prospective studies and retrospective studies of children with myopia treated with RGP lenses compared with spectacles, SCL, and OK lenses were included. Outcome measures were changes of axial length, spherical equivalent, flatter meridian, steeper meridian and corneal apical radius.
Five studies were included. Three studies reported axial length change after 2-3 years of treatment with RGP lenses and SCL/spectacles and no difference between the groups was noted (pooled mean difference = -0.077, 95% confidence interval [CI]: -0.120 to 0.097, p = 0.840). Two studies reported a change of spherical equivalent after 2-3 years of treatment with RGP lenses and SCL/spectacles, and no difference between the groups was noted (pooled mean difference = 0.275, 95% CI: -0.390 to 0.941, p = 0.417). Two studies compared corneal curvature measures between RGP and OK lenses after 3-6 months of treatment and no differences in any measures of corneal curvature were seen.
The effect of RGP lenses and SCL/spectacles on axial length elongation and spherical equivalent and of RGP and OK lenses on corneal curvature in children with myopia was similar.
本研究旨在进行一项荟萃分析，比较硬性透气性隐形眼镜（RGP）与软性隐形眼镜（SCL）、框架眼镜及角膜塑形术（OK）镜片在控制近视方面对眼轴长度延长、等效球镜度及角膜曲率测量值的影响。
检索了截至2015年9月29日的Medline、Cochrane、EMBASE和谷歌学术数据库，使用以下关键词：硬性透气性隐形眼镜；屈光不正；屈光异常。纳入了将RGP镜片治疗的近视儿童与框架眼镜、SCL及OK镜片进行比较的随机对照试验、双臂前瞻性研究和回顾性研究。观察指标为眼轴长度、等效球镜度、扁平子午线、陡峭子午线和角膜顶点半径的变化。
纳入了五项研究。三项研究报告了RGP镜片与SCL/框架眼镜治疗2 - 3年后的眼轴长度变化，两组之间未发现差异（合并平均差 = -0.077，95%置信区间[CI]：-0.120至0.097，p = 0.840）。两项研究报告了RGP镜片与SCL/框架眼镜治疗2 - 3年后的等效球镜度变化，两组之间未发现差异（合并平均差 = 0.275，95%CI：-0.390至0.941，p = 0.417）。两项研究比较了RGP与OK镜片治疗3 - 6个月后的角膜曲率测量值，未发现角膜曲率的任何测量值存在差异。
RGP镜片与SCL/框架眼镜对近视儿童眼轴长度延长和等效球镜度的影响，以及RGP与OK镜片对角膜曲率的影响相似。
