Parfitt Sheryl E, Bogat Mary L, Hering Sandra L, Roth Cheryl
Sheryl E. Parfitt is a Clinical Educator, HonorHealth Scottsdale Shea Medical Center, Scottsdale, AZ. The author can be reached via e-mail at
MCN Am J Matern Child Nurs. 2017 Jul/Aug;42(4):194-198. doi: 10.1097/NMC.0000000000000339.
In spite of many medical breakthroughs, sepsis continues to be challenging to identify, treat, and successfully resolve, including among the obstetric population. Sepsis is the result of an overactive, complex inflammatory response that is not completely understood. Currently there are no nationally agreed-upon criteria for systemic inflammatory response syndrome or sepsis in pregnant or peripartum women, as the physiologic changes of pregnancy have not been taken into consideration.This article is the first in a series of three that discuss the importance of sepsis and septic shock in pregnancy. The focus of this article is to understand the proposed pathophysiology of sepsis and new definitions associated with sepsis and septic shock. Knowledge of these conditions can assist in better identification of sepsis in the obstetric population.
尽管医学上取得了许多突破，但脓毒症的识别、治疗及成功解决仍然具有挑战性，在产科人群中亦是如此。脓毒症是一种过度活跃的复杂炎症反应的结果，而这种反应尚未被完全理解。目前，对于妊娠或围产期妇女的全身炎症反应综合征或脓毒症，尚无全国统一认可的标准，因为尚未考虑到妊娠的生理变化。本文是三篇系列文章中的第一篇，讨论脓毒症和脓毒性休克在妊娠中的重要性。本文的重点是了解脓毒症的拟议病理生理学以及与脓毒症和脓毒性休克相关的新定义。了解这些情况有助于更好地识别产科人群中的脓毒症。
