School of Chemistry, Monash University, Clayton, VIC 3800, Australia.
School of Chemistry, Monash University, Clayton, VIC 3800, Australia.
J Colloid Interface Sci. 2017 Nov 1;505:664-672. doi: 10.1016/j.jcis.2017.06.026. Epub 2017 Jun 8.
Robust silica microcapsules were synthesised using an emulsion template via a seeded growth strategy. Multiple additions of the silica precursor tetraethyl orthosilicate (TEOS) were observed to result in a number of physical and property changes of the capsule shells as compared to a single coating. Scanning electron microscopy indicated a morphological transition from a smooth to a roughened surface. Improved cargo retention and consolidation of the pore structure of the silica shells were observed using dye release experiments and nitrogen porosimetry respectively. In comparison to a typical hollow silica shell synthesis procedure, this one-pot loading and synthesis allows the simple production of robust capsules that are capable of sustained release, using mild conditions and reagents.
采用乳液模板和种子生长策略合成了坚固的二氧化硅微胶囊。与单次包覆相比，多次添加硅烷前驱体正硅酸乙酯（TEOS）会导致胶囊壳的一些物理和性能发生变化。扫描电子显微镜表明，从光滑表面到粗糙表面的形态转变。通过染料释放实验和氮气孔隙率分析分别观察到载物保留和二氧化硅壳孔结构的改善。与典型的空心二氧化硅壳合成工艺相比，这种一锅法负载和合成可以在温和的条件和试剂下，简单地生产出能够持续释放的坚固胶囊。
