Mansouritorghabeh Hassan, Rahimi Hossein, Mohades Seyed Tahereh, Behboudi Maryam
1 Allergy Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, School of Medicine, Mashhad, Iran.
2 Department of Hematology, Ghaem Hospital, Mashhad University of Medical Sciences, School of Medicine, Mashhad, Iran.
Clin Appl Thromb Hemost. 2018 May;24(4):612-617. doi: 10.1177/1076029617713873. Epub 2017 Jun 28.
There are steps to achieve an optimum life for patients with hemophilia in developing countries, and awareness of the pattern of death in patients with hemophilia is a prerequisite for any health-care program. Owing to the lack of any data on the pattern of death in patients with hemophilia from developing countries, the current study was done to address common causes of death, and the spectrum of causes of death among individuals with hemophilia A and B. To address the pattern of death in northeast of Iran, we retrospectively collected demographic data regarding deceased patients with hemophilia A and B. Overall, among 379 people with hemophilia A and B, there were 46 deaths. Thirty-two deaths happened in the severe forms of the diseases. The obtained results show the patterns of death in the patients studied are not as parallel as some reports from the developed countries. Traumatic and spontaneous bleeding events were the main causes of death. The trend of death shows a decrease in the current decade post better therapeutic facilities. Evaluation of causes of death in hemophilia can be a useful indicator for managing the efficacy of health care in the current patients.
在发展中国家，有一些步骤可以为血友病患者实现最佳生活，而了解血友病患者的死亡模式是任何医疗保健计划的先决条件。由于缺乏来自发展中国家血友病患者死亡模式的任何数据，本研究旨在探讨常见死因以及甲型和乙型血友病患者的死因谱。为了研究伊朗东北部的死亡模式，我们回顾性收集了甲型和乙型血友病死亡患者的人口统计学数据。总体而言，在379名甲型和乙型血友病患者中，有46人死亡。32例死亡发生在疾病的严重形式中。所得结果表明，所研究患者的死亡模式与一些发达国家的报告并不平行。创伤性和自发性出血事件是主要死因。死亡趋势显示，在有了更好的治疗设施后的当前十年中有所下降。评估血友病的死因可以作为管理当前患者医疗保健效果的有用指标。
