Takeuchi Nobuyuki, Kato Etushi, Kanemoto Kousuke
Neuropsychiatric Department, Aichi Medical University, Nagakute 480-1195, Japan.
Case Rep Psychiatry. 2017;2017:8164537. doi: 10.1155/2017/8164537. Epub 2017 Jun 1.
We report here a patient in whom the effects of a cerebellum mass may have led to development of obsessive-compulsive disorder (OCD). A 33-year-old woman showed symptoms of OCD, including obsessive worry about infection from tainted blood and repetitive confirmation, which worsened during pregnancy. She had comprehension in regard to her illness and no evidence of cognitive dysfunction and did not meet other DSM-5 criteria such as depression. One month after giving childbirth, the symptoms worsened, while headache and dizziness also developed. The Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) score was 34. The patient was examined for a headache and a posterior cranial fossa meningioma was found. Following resection of the meningioma, the OCD symptoms were remarkably reduced (Y-BOCS score 10). There is only one previous report of pure OCD associated with a cerebellar mass and the present findings should help to elucidate the mechanism.
我们在此报告一名患者，小脑肿块的影响可能导致了强迫症（OCD）的发生。一名33岁女性出现了强迫症症状，包括对受污染血液感染的强迫性担忧和反复确认，这些症状在怀孕期间加重。她对自己的病情有理解能力，没有认知功能障碍的证据，也不符合其他如抑郁症等DSM-5标准。分娩后一个月，症状加重，同时还出现了头痛和头晕。耶鲁-布朗强迫症量表（Y-BOCS）评分为34分。对该患者进行头痛检查时发现了后颅窝脑膜瘤。切除脑膜瘤后，强迫症症状明显减轻（Y-BOCS评分为10分）。此前仅有一篇关于与小脑肿块相关的单纯强迫症的报告，目前的研究结果应有助于阐明其机制。
