[与毒蝇伞中毒相关的肝脏损害形态学表现的独特特征]

[The peculiar features of the morphological manifestations of the damage to the liver associated with the death cap mushroom poisoning].

作者信息

Ivleva E A, Bogomolov D V, Putintsev V A, Bogomolova I N

机构信息

Belgorod Regional Bureau of Forensic Medical Expertise, Belgorod, Russia, 308017.

Federal state budgetary institution 'Russian Federal Centre of Forensic Medical Expertise', Ministry of Health of the Russia, Moscow, Russia, 125284.

出版信息

Sud Med Ekspert. 2017;60(3):23-26. doi: 10.17116/sudmed201760323-26.

DOI:10.17116/sudmed201760323-26

PMID:28656949

Abstract

This article is focused on the peculiar features of the morphological manifestations of massive hepatic necrosis associated with the death cap mushroom (Amanita phalloides) poisoning in comparison with similar cases of intoxication. It has been shown that the poisoning is associated with cell proliferation in the peri-portal regions of the liver and induction of the mechanisms of apoptosis responsible for the death of hepatocytes.

摘要

本文重点研究了与毒鹅膏中毒相关的大规模肝坏死形态学表现的独特特征，并与类似中毒病例进行了比较。研究表明，中毒与肝脏门静脉周围区域的细胞增殖以及导致肝细胞死亡的凋亡机制的诱导有关。