Castrovilli M C, Markush P, Bolognesi P, Rousseau P, Maclot S, Cartoni A, Delaunay R, Domaracka A, Kočišek J, Huber B A, Avaldi L
CNR-ISM, Area della Ricerca di Roma 1, Monterotondo Scalo, Italy.
Phys Chem Chem Phys. 2017 Aug 2;19(30):19807-19814. doi: 10.1039/c7cp02233f.
The fragmentation of the isolated 5-bromouracil (5BrU) molecule and pure and nano-hydrated 5BrU clusters induced by low energy C ions has been studied. A comparison indicates that the environment, on the one hand, protects the system against the complete break-up into small fragments, but, on the other hand, triggers 'new' pathways for fragmentation, for example the loss of the OH group. The most striking result is the observation of several series of hydrated fragments in the hydrated cluster case, with water molecules bound to hydrophilic sites of 5BrU. This highlights the strong interaction between 5BrU and water molecules and the blocking of specific fragmentation pathways, such as the loss of the BrCH group for example.
研究了低能C离子诱导的孤立5-溴尿嘧啶（5BrU）分子以及纯的和纳米水合5BrU团簇的碎片化过程。比较结果表明，一方面，环境可保护系统不致完全分解成小碎片，但另一方面，也会引发“新的”碎片化途径，例如OH基团的损失。最显著的结果是在水合团簇情况下观察到了几系列水合碎片，水分子与5BrU的亲水位点结合。这突出了5BrU与水分子之间的强相互作用以及特定碎片化途径的受阻，例如BrCH基团的损失。
