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经黏膜下隧道内镜切除术治疗食管和胃底部贲门附近的黏膜下肿瘤。

Modified submucosal tunneling endoscopic resection for submucosal tumors in the esophagus and gastric fundus near the cardia.

机构信息

Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Shenzhen Digestive Disease Medical Center, Nanfang Hospital, Southern Medical University, Shenzhen Longgang District People's Hospital, Shenzhen, China.

出版信息

Endoscopy. 2017 Aug;49(8):784-791. doi: 10.1055/s-0043-111236. Epub 2017 Jun 28.

Abstract

Submucosal tunneling endoscopic resection with double opening (DO-STER) was developed by our group for the resection of submucosal tumors in the esophagus and gastric fundus near the cardia. This study aimed to provide a preliminary evaluation of feasibility and safety of DO-STER.  The key to DO-STER is the creation of a tunnel opening in the mucosa over the inferior border of the tumor. During resection, the tumor can be gradually pushed out of the submucosal tunnel through the opening, leaving enough space for operation within the tunnel. A total of 10 tumors resected by DO-STER were retrospectively reviewed.  All tumors were successfully resected by DO-STER. One tumor was located at the lower esophagus, four at the esophagogastric junction, and five at the gastric fundus near the cardia. Tumor size ranged from 1.0 × 1.2 cm to 3.5 × 5.0 cm, and all tumors originated from the muscularis propria. Operative times ranged from 45 to 150 minutes. No delayed bleeding or perforation occurred. DO-STER seems to provide an alternative approach for resection of tumors in the esophagus and gastric fundus near the cardia.

摘要

黏膜下隧道内镜切除术(DO-STER)由我们团队开发,用于切除食管和胃底部贲门附近的黏膜下肿瘤。本研究旨在初步评估 DO-STER 的可行性和安全性。DO-STER 的关键是在肿瘤下缘的黏膜上创建一个隧道开口。在切除过程中,肿瘤可以通过开口逐渐推出黏膜下隧道,为隧道内的操作留出足够的空间。共回顾性分析了 10 例经 DO-STER 切除的肿瘤。所有肿瘤均成功通过 DO-STER 切除。其中 1 例位于食管下段,4 例位于食管胃交界处,5 例位于胃底部贲门附近。肿瘤大小为 1.0×1.2cm 至 3.5×5.0cm,均起源于固有肌层。手术时间为 45-150 分钟。无迟发性出血或穿孔发生。DO-STER 似乎为食管和胃底部贲门附近肿瘤的切除提供了一种替代方法。

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