Bhatia Nitin, Rama Asheen, Sievers Brandon, Quigley Ryan, McGarry Michelle H, Lee Yu-Po, Lee Thay Q
University of California, Irvine, CA, USA.
VA Long Beach Healthcare System, Irvine, CA, USA.
Global Spine J. 2017 May;7(3):239-245. doi: 10.1177/2192568217694152. Epub 2017 Apr 7.
Biomechanical, cadaveric study.
To compare the relative stiffness of unilateral C1 lateral mass-C2 intralaminar fixation to intact specimens and bilateral C1 lateral mass-C2 intralaminar constructs.
The biomechanical integrity of a unilateral C1 lateral mass-C2 intralaminar screw construct was compared to intact specimens and bilateral C1 lateral mass-C2 intralaminar screw constructs. Five human cadaveric specimens were used. Range of motion and stiffness were tested to determine the stiffness of the constructs.
Unilateral fixation significantly decreased flexion/extension range of motion compared to intact ( < .001) but did not significantly affect axial rotation ( = .3) or bending range of motion ( = .3). There was a significant decrease in stiffness in extension for both unilateral and bilateral fixation techniques compared to intact ( = .04 and = .03, respectively). There was also a significant decrease in stiffness for ipsilateral rotation for the unilateral construct compared to intact ( = .007) whereas the bilateral construct significantly increased ipsilateral rotation stiffness compared to both intact and unilateral fixation ( < .001).
Bilateral constructs did show improved biomechanical properties compared to the unilateral constructs. However, unilateral C1-C2 fixation using a C1 lateral mass and C2 intralaminar screw-rod construct decreased range of motion and improved stiffness compared to the intact state with the exception of extension and ipsilateral rotation. Hence, a unilateral construct may be acceptable in clinical situations in which bilateral fixation is not possible, but an external orthosis may be necessary to achieve a fusion.
生物力学尸体研究。
比较单侧C1侧块-C2椎板内固定与完整标本及双侧C1侧块-C2椎板内固定结构的相对刚度。
将单侧C1侧块-C2椎板内螺钉结构的生物力学完整性与完整标本及双侧C1侧块-C2椎板内螺钉结构进行比较。使用了5具人类尸体标本。测试运动范围和刚度以确定结构的刚度。
与完整标本相比,单侧固定显著降低了屈伸运动范围(P <.001),但对轴向旋转(P =.3)或侧弯运动范围(P =.3)无显著影响。与完整标本相比,单侧和双侧固定技术在伸展时的刚度均显著降低(分别为P =.04和P =.03)。与完整标本相比,单侧结构同侧旋转的刚度也显著降低(P =.007),而双侧结构与完整标本和单侧固定相比,同侧旋转刚度均显著增加(P <.001)。
与单侧结构相比,双侧结构确实显示出更好的生物力学性能。然而,使用C1侧块和C2椎板内螺钉-棒结构的单侧C1-C2固定与完整状态相比,除伸展和同侧旋转外,运动范围减小,刚度提高。因此,在无法进行双侧固定的临床情况下,单侧结构可能是可以接受的,但可能需要外部矫形器来实现融合。