Kirby G C, Faulconer E R, Robinson S J, Perry A, Downing R
Department of Upper Gastrointestinal Surgery, Worcestershire Acute Hospitals NHS Trust , Worcester , UK.
Department of Vascular Surgery, Worcestershire Acute Hospitals NHS Trust , Worcester , UK.
Ann R Coll Surg Engl. 2017 Jul;99(6):472-475. doi: 10.1308/rcsann.2017.0063.
INTRODUCTION The superior mesenteric artery (SMA) syndrome, or Wilkie's syndrome, is a rare cause of postprandial epigastric pain, vomiting and weight loss caused by compression of the third part of the duodenum as it passes beneath the proximal superior mesenteric artery. The syndrome may be precipitated by sudden weight loss secondary to other pathologies, such as trauma, malignancy or eating disorders. Diagnosis is confirmed by angiography, which reveals a reduced aorto-SMA angle and distance, and contrast studies showing duodenal obstruction. Conservative management aims to increase intra-abdominal fat by dietary manipulation and thereby increase the angle between the SMA and aorta. Where surgery is indicated, division of the ligament of Treitz, anterior transposition of the third part of the duodenum and duodenojejunostomy have been described. METHODS We present four cases of SMA syndrome where the intention of treatment was laparoscopic duodenojejunostomy. The procedure was completed successfully in three patients, who recovered quickly with no short-term complications. A fourth patient underwent open gastrojejunostomy (complicated by an anastomotic bleed) when dense adhesions prevented duodenojejunostomy. CONCLUSIONS The superior mesenteric artery syndrome should be considered in patients with epigastric pain, prolonged vomiting and weight loss. Laparoscopic duodenojejunostomy is a safe and effective operation for management of the syndrome. A multi-speciality team approach including gastrointestinal, vascular and radiological specialists should be invoked in the management of these patients.
引言 肠系膜上动脉(SMA)综合征,即威尔基综合征,是一种餐后上腹部疼痛、呕吐和体重减轻的罕见病因,是由于十二指肠第三部在肠系膜上动脉近端下方通过时受到压迫所致。该综合征可能由其他病理状况继发的体重突然减轻所诱发,如创伤、恶性肿瘤或饮食失调。血管造影显示腹主动脉-肠系膜上动脉夹角和距离减小,对比研究显示十二指肠梗阻,可确诊该综合征。保守治疗旨在通过饮食调整增加腹腔内脂肪,从而增大肠系膜上动脉与腹主动脉之间的夹角。如需手术治疗,已有人描述过切断Treitz韧带、十二指肠第三部前移和十二指肠空肠吻合术。
方法 我们报告4例肠系膜上动脉综合征患者,其治疗目的是行腹腔镜十二指肠空肠吻合术。3例患者手术成功完成,恢复迅速,无短期并发症。第4例患者因致密粘连无法行十二指肠空肠吻合术,接受了开放式胃空肠吻合术(并发吻合口出血)。
结论 对于有上腹部疼痛、长期呕吐和体重减轻的患者,应考虑肠系膜上动脉综合征。腹腔镜十二指肠空肠吻合术是治疗该综合征的一种安全有效的手术方法。在这些患者的管理中,应调用包括胃肠、血管和放射科专家在内的多专业团队方法。