Nacca Christopher R, Harris Andrew P, Tuttle John R
Orthopedics. 2017 Nov 1;40(6):e940-e946. doi: 10.3928/01477447-20170619-05. Epub 2017 Jun 30.
The musculoskeletal manifestations of hemophilia A and B are some of the most common presenting symptoms and continue to be challenging to practitioners. Hemophilic arthropathy, if not initially adequately treated and managed, may lead to debilitating disease and eventually require the consideration of major surgery, including total joint arthroplasty. Thorough comprehension of the pathophysiology, diagnosis, and both medical and surgical interventions is critical in establishing an appropriate treatment regimen for these patients. Furthermore, a true multidisciplinary approach involving hematology, orthopedics, and physical therapy is essential for a patient with hemophilic arthropathy. The authors present a comprehensive review of hemophilic arthropathy from an orthopedist's perspective. [Orthopedics. 2017; 40(6):e940-e946.].
甲型和乙型血友病的肌肉骨骼表现是一些最常见的症状，并且仍然给从业者带来挑战。血友病性关节病，如果最初没有得到充分的治疗和管理，可能会导致使人衰弱的疾病，最终可能需要考虑进行包括全关节置换术在内的大手术。深入理解病理生理学、诊断以及药物和手术干预对于为这些患者制定合适的治疗方案至关重要。此外，对于血友病性关节病患者，真正的多学科方法，包括血液学、骨科和物理治疗，是必不可少的。作者从骨科医生的角度对血友病性关节病进行了全面综述。[《骨科》。2017年；40(6):e940 - e946。]
