使用自动六点狄克逊法进行肝脏脂肪定量：与传统化学位移序列及计算机断层扫描的比较
Hepatic fat quantification using automated six-point Dixon: Comparison with conventional chemical shift based sequences and computed tomography.
作者信息
Shimizu Kie, Namimoto Tomohiro, Nakagawa Masataka, Morita Kosuke, Oda Seitaro, Nakaura Takeshi, Utsunomiya Daisuke, Yamashita Yasuyuki
机构信息
Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, 1-1-1, Honjo, Chuoku, Kumamoto 860-8556, Japan.
Department of Diagnostic Radiology, Graduate School of Life Sciences, Kumamoto University, 1-1-1, Honjo, Chuoku, Kumamoto 860-8556, Japan.
出版信息
Clin Imaging. 2017 Sep-Oct;45:111-117. doi: 10.1016/j.clinimag.2017.06.006. Epub 2017 Jun 20.
PURPOSE
To compare automated six-point Dixon (6-p-Dixon) MRI comparing with dual-echo chemical-shift-imaging (CSI) and CT for hepatic fat fraction in phantoms and clinical study.
MATERIALS AND METHODS
Phantoms and fifty-nine patients were examined both MRI and CT for quantitative fat measurements.
RESULTS
In phantom study, linear regression between fat concentration and 6-p-Dixon showed good agreement. In clinical study, linear regression between 6-p-Dixon and dual-echo CSI showed good agreement. CT attenuation value was strongly correlated with 6-p-Dixon (R=0.852; P<0.001) and dual-echo CSI (R=0.812; P<0.001).
CONCLUSION
Automated 6-p-Dixon and dual-echo CSI were accurate correlation with CT attenuation value of liver parenchyma. 6-p-Dixon has the potential for automated hepatic fat quantification.
目的
在体模和临床研究中，比较自动六点狄克逊（6-p-狄克逊）磁共振成像（MRI）与双回波化学位移成像（CSI）及CT用于测量肝脏脂肪分数的情况。
材料与方法
对体模和59例患者进行了MRI和CT检查以进行脂肪定量测量。
结果
在体模研究中，脂肪浓度与6-p-狄克逊之间的线性回归显示出良好的一致性。在临床研究中，6-p-狄克逊与双回波CSI之间的线性回归显示出良好的一致性。CT衰减值与6-p-狄克逊（R = 0.852；P < 0.001）和双回波CSI（R = 0.812；P < 0.001）密切相关。
结论
自动6-p-狄克逊和双回波CSI与肝实质的CT衰减值具有准确的相关性。6-p-狄克逊具有实现肝脏脂肪自动定量的潜力。
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