Coker Jessica L, Tripathi Shanti P, Knight Bettina T, Pennell Page B, Magann Everett F, Newport D Jeffrey, Stowe Zachary N
Department of Psychiatry, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, AR, 72205, USA.
Psychiatric Research Institute, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, AR, 72205, USA.
Arch Womens Ment Health. 2017 Oct;20(5):687-694. doi: 10.1007/s00737-017-0749-2. Epub 2017 Jun 30.
We examined the utility of screening instruments to identify risk factors for suicidal ideation (SI) in a population of women with neuropsychiatric illnesses at high risk for postpartum depression. Pregnant women with neuropsychiatric illness enrolled prior to 20 weeks of gestation. Follow-up visits at 4-8-week intervals through 13 weeks postpartum included assessment of depressive symptoms with both clinician and self-rated scales. A total of 842 women were included in the study. Up to 22.3% of postpartum women admitted SI on rating scales, despite the majority (79%) receiving active pharmacological treatment for psychiatric illness. Postpartum women admitting self-harm/SI were more likely to meet criteria for current major depressive episode (MDE), less than college education, an unplanned pregnancy, a history of past suicide attempt, and a higher score on the Childhood Trauma Questionnaire. In women with a history of neuropsychiatric illness, over 20% admitted SI during the postpartum period despite ongoing psychiatric treatment. Patient-rated depression scales are more sensitive screening tools than a clinician-rated depression scale for +SI in the postpartum period.
我们研究了筛查工具在识别产后抑郁症高危神经精神疾病女性群体中自杀意念(SI)风险因素方面的效用。患有神经精神疾病的孕妇在妊娠20周之前入组。产后13周内每隔4 - 8周进行一次随访,包括使用临床医生评定量表和自评量表评估抑郁症状。共有842名女性纳入本研究。尽管大多数(79%)接受了针对精神疾病的积极药物治疗,但高达22.3%的产后女性在评定量表上承认有自杀意念。承认有自我伤害/自杀意念的产后女性更有可能符合当前重度抑郁发作(MDE)的标准、受教育程度低于大学、意外怀孕、有既往自杀未遂史以及在儿童创伤问卷上得分更高。在有神经精神疾病史的女性中,超过20%的人尽管正在接受精神科治疗,但在产后期间仍承认有自杀意念。在产后期间,患者自评抑郁量表比临床医生评定抑郁量表对自杀意念的筛查更敏感。