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HIV 感染孕妇的血压、抑郁和自杀意念。

Blood Pressure, Depression, and Suicidal Ideation Among Pregnant Women with HIV.

机构信息

Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, 1400 NW 10th Ave., Suite 404A, Miami, FL, 33136, USA.

Department of Psychology, University of Georgia, Athens, GA, USA.

出版信息

AIDS Behav. 2022 Apr;26(4):1289-1298. doi: 10.1007/s10461-021-03486-4. Epub 2021 Oct 14.

Abstract

Although prior research has examined associations between blood pressure (BP), depression, and suicidal ideation, few studies have examined this in high-risk populations such as pregnant women with HIV (WHIV). The current study examined the association of BP with depression and suicidal ideation among pregnant WHIV (n = 217) in rural South Africa. BP data (measured ≤ 1 month before the study visit) was extracted from medical records. Depressive symptomatology and suicidal ideation were assessed using the Edinburgh Postnatal Depression Scale. Diastolic BP was positively associated with both suicidal ideation and depressive symptomatology, even after controlling for demographic variables, gestational age, and intimate partner violence. These findings suggest that WHIV with elevated BP may be at greater risk for antenatal depression and suicidal ideation. Future research should utilize longitudinal designs to examine potential mechanisms and the directionality of the relationship, as well as other contributing factors.

摘要

尽管先前的研究已经检验了血压(BP)、抑郁和自杀意念之间的关联,但很少有研究在高危人群(如感染 HIV 的孕妇)中进行此类研究。本研究在南非农村地区调查了妊娠 HIV 阳性妇女(WHIV,n=217)中 BP 与抑郁和自杀意念之间的关联。BP 数据(在研究就诊前≤1 个月内测量)从病历中提取。使用爱丁堡产后抑郁量表评估抑郁症状和自杀意念。即使在控制了人口统计学变量、孕龄和亲密伴侣暴力后,舒张压仍与自杀意念和抑郁症状呈正相关。这些发现表明,血压升高的 WHIV 可能面临更大的产前抑郁和自杀意念风险。未来的研究应该采用纵向设计来检查潜在的机制和关系的方向性,以及其他相关因素。

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