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1
Influence of OATP1B1 Function on the Disposition of Sorafenib-β-D-Glucuronide.OATP1B1 功能对索拉非尼-β-D-葡糖苷酸处置的影响。
Clin Transl Sci. 2017 Jul;10(4):271-279. doi: 10.1111/cts.12458. Epub 2017 Mar 31.
2
Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.索拉非尼葡糖醛酸的肝细胞穿梭和再循环依赖于Abcc2、Abcc3和Oatp1a/1b。
Cancer Res. 2015 Jul 1;75(13):2729-36. doi: 10.1158/0008-5472.CAN-15-0280. Epub 2015 May 7.
3
Hepatocyte hopping of OATP1B substrates contributes to efficient hepatic detoxification.OATP1B底物的肝细胞跳跃有助于高效的肝脏解毒。
Clin Pharmacol Ther. 2012 Nov;92(5):559-62. doi: 10.1038/clpt.2012.143. Epub 2012 Sep 26.
4
Sorafenib in advanced melanoma: a critical role for pharmacokinetics?索拉非尼治疗晚期黑色素瘤：药代动力学的关键作用？
Br J Cancer. 2012 Jul 24;107(3):455-61. doi: 10.1038/bjc.2012.287. Epub 2012 Jul 5.
5
Variability of sorafenib toxicity and exposure over time: a pharmacokinetic/pharmacodynamic analysis.索拉非尼毒性和暴露随时间的变化：药代动力学/药效学分析。
Oncologist. 2012;17(9):1204-12. doi: 10.1634/theoncologist.2011-0439. Epub 2012 Jul 2.
6
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.索拉非尼治疗实体瘤患者的群体药代动力学分析。
Br J Clin Pharmacol. 2011 Aug;72(2):294-305. doi: 10.1111/j.1365-2125.2011.03963.x.
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Pharmacokinetic modeling of the hepatobiliary transport mediated by cooperation of uptake and efflux transporters.经摄取转运体和外排转运体协同作用介导的肝胆转运的药代动力学模型。
Drug Metab Rev. 2010 Aug;42(3):539-50. doi: 10.3109/03602530903491824.
8
Predicting in vivo drug interactions from in vitro drug discovery data.从体外药物发现数据预测体内药物相互作用。
Nat Rev Drug Discov. 2005 Oct;4(10):825-33. doi: 10.1038/nrd1851.
9
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.细胞色素P450 3A和P-糖蛋白的重叠底物特异性及组织分布：对癌症化疗中药物递送和活性的影响
Mol Carcinog. 1995 Jul;13(3):129-34. doi: 10.1002/mc.2940130302.

Commentary on: "Influence of OATP1B1 Function on the Disposition of Sorafenib-β-D-Glucuronide".

作者信息

Morrissey K M, Benet L Z, Ware J A

机构信息

Department of Clinical Pharmacology, Genentech, Inc., South San Francisco, California, USA.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA.

出版信息

Clin Transl Sci. 2017 Jul;10(4):240-241. doi: 10.1111/cts.12476. Epub 2017 Jun 29.

DOI:10.1111/cts.12476
PMID:28664655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5504478/
Abstract
摘要