Sander Ruth
Nurs Older People. 2017 Jun 30;29(6):11. doi: 10.7748/nop.29.6.11.s13.
Atrial fibrillation is associated with an increased risk of ischaemic stroke and mortality. Guidelines recommend non-vitamin K antagonist oral anticoagulants, or novel oral anticoagulants, as first choice of drug. While they do not require the meticulous dose adjustments that are required for warfarin, a clinical evaluation of appropriate dose is still necessary. Age and chronic kidney disease in patients with atrial fibrillation increase the risk of bleeding during anti-thrombotic treatment.
心房颤动与缺血性中风和死亡风险增加相关。指南推荐非维生素K拮抗剂口服抗凝药或新型口服抗凝药作为首选药物。虽然它们不像华法林那样需要精确的剂量调整，但仍有必要对合适的剂量进行临床评估。心房颤动患者的年龄和慢性肾脏病会增加抗栓治疗期间出血的风险。
