Alferova V V, Mayorova L A, Ivanova E G, Guekht A B, Shklovskij V M
Center for Speech Pathology and Neurorehabilitation, Moscow, Russia; Pirogov Russian National Research Medical University, Moscow, Russia.
Center for Speech Pathology and Neurorehabilitation, Moscow, Russia; Institute of Higher Nervous Activity of RAS, Moscow, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(3. Vyp. 2):71-78. doi: 10.17116/jnevro20171173271-78.
The introduction of non-invasive functional neuroimaging techniques such as functional magnetic resonance imaging (fMRI), in the practice of scientific and clinical research can increase our knowledge about the organization of cognitive processes, including language, in normal and reorganization of these cognitive functions in post-stroke aphasia. The article discusses the results of fMRI studies of functional organization of the cortex of a healthy adult's brain in the processing of various voice information as well as the main types of speech reorganization after post-stroke aphasia in different stroke periods. The concepts of 'effective' and 'ineffective' brain plasticity in post-stroke aphasia were considered. It was concluded that there was an urgent need for further comprehensive studies, including neuropsychological testing and several complementary methods of functional neuroimaging, to develop a phased treatment plan and neurorehabilitation of patients with post-stroke aphasia.
诸如功能磁共振成像（fMRI）等无创性功能神经成像技术在科学和临床研究实践中的引入，可以增加我们对认知过程组织的了解，包括正常情况下的语言以及中风后失语症中这些认知功能的重组。本文讨论了功能磁共振成像研究健康成人大脑皮质在处理各种语音信息时的功能组织结果，以及不同中风时期中风后失语症后言语重组的主要类型。文中还探讨了中风后失语症中“有效”和“无效”脑可塑性的概念。得出的结论是，迫切需要进一步进行全面研究，包括神经心理学测试和几种功能性神经成像的补充方法，以制定中风后失语症患者的分阶段治疗计划和神经康复方案。
