Shatar Munkhduuren, Khanui Buyantogtokh, Purevtseren Dulam, Khishgee Bodisaikhan, Loitsch Angelika, Unger Hermann, Settypalli Tirumala B K, Cattoli Giovanni, Damdinjav Batchuluun, Dundon William G
State Central Veterinary Laboratory, Khan-Uul district, Post Box 53/03, Ulaanbaatar, 17024, Mongolia.
Institute for Veterinary Disease Control, Austrian Agency for Health and Food Safety, Mödling, Austria.
Arch Virol. 2017 Oct;162(10):3157-3160. doi: 10.1007/s00705-017-3456-4. Epub 2017 Jun 30.
Between August and September 2016 pathological samples were collected from sheep and goats following suspected peste des petits ruminants (PPR) outbreaks in western Mongolia. RT-PCR followed by sequencing and phylogenetic analysis of the samples confirmed the presence of a PPR virus belonging to lineage IV. A full genome analysis of the viral RNA from one of the samples revealed a high similarity (99.0-99.5%) with PPR viruses currently circulating in China (2013-2015) indicating a common origin. This is the first genetic characterization of PPR virus in Mongolia and the data generated will have important implications for control and management of the disease in the region.
2016年8月至9月期间,在蒙古西部疑似发生小反刍兽疫(PPR)疫情后,从绵羊和山羊身上采集了病理样本。对样本进行逆转录聚合酶链反应(RT-PCR),随后进行测序和系统发育分析,证实存在属于IV系的小反刍兽疫病毒。对其中一个样本的病毒RNA进行全基因组分析,结果显示与目前在中国流行的小反刍兽疫病毒(2013 - 2015年)具有高度相似性(99.0 - 99.5%),表明有共同起源。这是蒙古首次对小反刍兽疫病毒进行基因特征分析,所产生的数据将对该地区疾病的控制和管理具有重要意义。