Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Ehime, Japan.
Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Ehime, Japan.
J Diabetes Investig. 2018 Mar;9(2):279-285. doi: 10.1111/jdi.12709. Epub 2017 Aug 14.
AIMS/INTRODUCTION: No reports have been published on the association between dietary intake habits and nocturia in the diabetes population. We therefore evaluated this issue among Japanese patients with diabetes mellitus.
Study participants in the present study were 785 Japanese patients with type 2 diabetes mellitus. Self-administered questionnaires were used to assess each type of dietary intake habit. Vegetable intake habit was assessed by the following question: "Do you have vegetables or seaweed every day?" We used the following two outcomes: (i) nocturia: ≥2 voids per night; and (ii) severe nocturia: ≥3 voids per night. Adjustment was made for age, sex, body mass index, glycated hemoglobin, hypertension, dyslipidemia, smoking, drinking, exercise habit, stroke, ischemic artery disease, diabetic nephropathy, diabetic neuropathy and diabetic retinopathy.
The prevalence of nocturia, severe nocturia, and vegetable intake habit was 39.9%, 14.4% and 67.3%, respectively. After adjusting for confounding factors, vegetable intake habit was independently inversely associated with nocturia and severe nocturia: the adjusted odds ratios were 0.67 (95% confidence interval [CI] 0.48-0.94) and 0.46 (95% CI 0.30-0.71), respectively. Among male patients, vegetable intake habit was independently inversely associated with severe nocturia, but not nocturia: the adjusted OR was 0.51 (95% CI 0.29-0.88). Among female patients, vegetable intake habit was independently inversely associated with nocturia and severe nocturia: the adjusted ORs were 0.44 (95% CI 0.24-0.79) and 0.34 (95% CI 0.15-0.78), respectively.
We found an inverse association between vegetable intake habit and nocturia in Japanese patients with type 2 diabetes mellitus.
目的/引言：目前尚无报告显示糖尿病患者的饮食摄入习惯与夜尿症之间存在关联。因此，我们评估了日本 2 型糖尿病患者的这一问题。
本研究的研究对象为 785 名日本 2 型糖尿病患者。采用自填式问卷评估每种饮食摄入习惯。蔬菜摄入习惯通过以下问题进行评估：“你每天都吃蔬菜或海藻吗？”我们使用以下两个结果：（i）夜尿症：≥2 次/晚；（ii）严重夜尿症：≥3 次/晚。调整了年龄、性别、体重指数、糖化血红蛋白、高血压、血脂异常、吸烟、饮酒、运动习惯、中风、缺血性动脉疾病、糖尿病肾病、糖尿病周围神经病变和糖尿病视网膜病变。
夜尿症、严重夜尿症和蔬菜摄入习惯的患病率分别为 39.9%、14.4%和 67.3%。在调整了混杂因素后，蔬菜摄入习惯与夜尿症和严重夜尿症呈独立负相关：调整后的比值比分别为 0.67（95%置信区间 [CI] 0.48-0.94）和 0.46（95% CI 0.30-0.71）。在男性患者中，蔬菜摄入习惯与严重夜尿症独立负相关，但与夜尿症无关：调整后的比值比为 0.51（95% CI 0.29-0.88）。在女性患者中，蔬菜摄入习惯与夜尿症和严重夜尿症独立负相关：调整后的比值比分别为 0.44（95% CI 0.24-0.79）和 0.34（95% CI 0.15-0.78）。
我们发现日本 2 型糖尿病患者的蔬菜摄入习惯与夜尿症之间存在负相关。
