Jamali Akram, Sadeghi-Demneh Ebrahim, Fereshtenajad Niloufar, Hillier Susan
Musculoskeletal Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; Research Committee of Rehabilitation Students (Treata), Isfahan University of Medical Sciences, Isfahan, Iran.
Musculoskeletal Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Gait Posture. 2017 Sep;57:224-229. doi: 10.1016/j.gaitpost.2017.06.020. Epub 2017 Jun 24.
Somatosensory impairments are common in multiple sclerosis. However, little data are available to characterize the nature and frequency of these problems in people with multiple sclerosis.
To investigate the frequency of somatosensory impairments and identify any association with balance limitations in people with multiple sclerosis.
The design was a prospective cross-sectional study, involving 82 people with multiple sclerosis and 30 healthy controls. Tactile and proprioceptive sensory acuity were measured using the Rivermead Assessment of Somatosensory Performance. Vibration duration was assessed using a tuning fork. Duration for the Timed Up and Go Test and reaching distance of the Functional Reach Test were measured to assess balance limitations. The normative range of sensory modalities was defined using cut-off points in the healthy participants. The multivariate linear regression was used to identify the significant predictors of balance in people with multiple sclerosis.
Proprioceptive impairments (66.7%) were more common than tactile (60.8%) and vibration impairments (44.9%). Somatosensory impairments were more frequent in the lower limb (78.2%) than the upper limb (64.1%). All sensory modalities were significantly associated with the Timed Up and Go and Functional Reach tests (p<0.05). The Timed Up and Go test was independently predicted by the severity of the neurological lesion, Body Mass Index, ataxia, and tactile sensation (R2=0.58), whereas the Functional Reach test was predicted by the severity of the neurological lesion, lower limb strength, and vibration sense (R2=0.49).
Somatosensory impairments are very common in people with multiple sclerosis. These impairments are independent predictors of balance limitation.
体感障碍在多发性硬化症中很常见。然而，关于多发性硬化症患者这些问题的性质和频率的可用数据很少。
调查多发性硬化症患者体感障碍的频率，并确定其与平衡受限之间的任何关联。
该设计为前瞻性横断面研究，纳入82例多发性硬化症患者和30名健康对照者。使用Rivermead体感功能评估量表测量触觉和本体感觉敏锐度。使用音叉评估振动持续时间。测量计时起立行走测试的持续时间和功能性伸展测试的伸展距离，以评估平衡受限情况。通过健康参与者的截断点定义感觉模式的正常范围。采用多元线性回归确定多发性硬化症患者平衡的显著预测因素。
本体感觉障碍（66.7%）比触觉障碍（60.8%）和振动障碍（44.9%）更常见。下肢的体感障碍（78.2%）比上肢（64.1%）更频繁。所有感觉模式均与计时起立行走测试和功能性伸展测试显著相关（p<0.05）。计时起立行走测试由神经病变的严重程度、体重指数、共济失调和触觉感觉独立预测（R2=0.58），而功能性伸展测试由神经病变的严重程度、下肢力量和振动觉预测（R2=0.49）。
体感障碍在多发性硬化症患者中非常常见。这些障碍是平衡受限的独立预测因素。
