Doherty J E
Cardiology. 1985;72(5-6):225-54. doi: 10.1159/000173883.
Digitalis glycosides continue to place high on the list of prescribed drugs. Digoxin is 8th on prescriptions written in the United States in 1980, digitoxin 16th, and digitalis leaf 23rd. There is little doubt that most physicians continue to believe these drugs are useful. The application of more definite indications, smaller doses, and the recognition of the role of pharmacokinetics and drug interactions make use of the glycosides more challenging than ever before in 1985.
洋地黄苷类药物仍然是常用处方药中的热门品种。地高辛在1980年美国的处方用药中排第8位,洋地黄毒苷排第16位,洋地黄叶排第23位。毫无疑问,大多数医生仍然认为这些药物是有用的。1985年,更明确的适应证、更小的剂量以及对药代动力学和药物相互作用的认识,使得洋地黄苷类药物的应用比以往任何时候都更具挑战性。