微红颤藻产生双去甲基化微囊藻毒素变体。
Production of a bisdemethylated microcystin variant by Planktothrix rubescens.
作者信息
Zoschke Kristin, Schübel Marta, Börnick Hilmar, Worch Eckhard
机构信息
Technische Universität Dresden, Institute of Water Chemistry, D-01062, Dresden, Germany.
Technische Universität Dresden, Institute of Water Chemistry, D-01062, Dresden, Germany.
出版信息
Toxicon. 2017 Oct;137:95-98. doi: 10.1016/j.toxicon.2017.06.015. Epub 2017 Jun 29.
Reservoir samples from a bloom of Planktothrix rubescens were analyzed by ELISA and LC-MS/MS. The comparison of the results of both methods points to the presence of a microcystin variant not yet available as analytical standard and therefore, not detectable by LC-MS/MS analysis. It is proposed that the unknown cyanotoxin variant is a bisdemethylated microcystin variant, presumably [Asp,Dha]-microcystin-RR. [Asp,Dha]-MC-RR has not been described for a bloom of P. rubescens before.
采用酶联免疫吸附测定法（ELISA）和液相色谱-串联质谱法（LC-MS/MS）对来自微红颤藻水华的储样进行了分析。两种方法的结果比较表明，存在一种尚未作为分析标准品的微囊藻毒素变体，因此无法通过LC-MS/MS分析检测到。据推测，未知的蓝藻毒素变体是一种双去甲基化微囊藻毒素变体，可能是[天冬氨酸，脱氢丙氨酸]-微囊藻毒素-RR。此前尚未有关于微红颤藻水华出现[天冬氨酸，脱氢丙氨酸]-微囊藻毒素-RR的报道。
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