A comparative study of monooxygenase activity in elasmobranchs and mammals: activation of the model pro-carcinogen aflatoxin B1 by liver preparations of calf, nurse shark and clearnose skate.
作者信息
Bodine A B, Luer C A, Gangjee S
出版信息
Comp Biochem Physiol C Comp Pharmacol Toxicol. 1985;82(2):255-7. doi: 10.1016/0742-8413(85)90159-8.
PMID:2866897
Abstract
Liver microsome preparations of the elasmobranchs Ginglymostoma cirratum (nurse shark) and Raja eglanteria (clearnose skate) were examined for monooxygenase activity using aflatoxin B1 as substrate. At equiprotein concentrations, elasmobranch microsomes were less than 20% as active as calf liver in producing mutagenic metabolites of aflatoxin B1.
摘要
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A comparative study of monooxygenase activity in elasmobranchs and mammals: activation of the model pro-carcinogen aflatoxin B1 by liver preparations of calf, nurse shark and clearnose skate.
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