New Insight of OCT2 Regulation as Mediator for Cisplatin- Induced Nephrotoxicity.
作者信息
EL-Arabey Amr Ahmed, Abdalla Mohnad
机构信息
Pharmacology and Toxicology Department, Faculty of Pharmacy, Al-Azhar University, Egypt. Email:
CAS-TWAS Fellowship at University of Science and Technology of China (USTC), China.
出版信息
Asian Pac J Cancer Prev. 2017 Jun 25;18(6):1459-1460. doi: 10.22034/APJCP.2017.18.6.1459.
Abstract
摘要
相似文献
1
New Insight of OCT2 Regulation as Mediator for Cisplatin- Induced Nephrotoxicity.OCT2调控作为顺铂诱导肾毒性介质的新见解。
Asian Pac J Cancer Prev. 2017 Jun 25;18(6):1459-1460. doi: 10.22034/APJCP.2017.18.6.1459.
2
Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity.有机阳离子转运体2（OCT2）在顺铂诱导的肾毒性中的作用。
Clin Pharmacol Ther. 2009 Oct;86(4):396-402. doi: 10.1038/clpt.2009.139. Epub 2009 Jul 22.
3
Strong inhibition of organic cation transporter 2 by flavonoids and attenuation effects on cisplatin-induced cytotoxicity.黄酮类化合物对有机阳离子转运蛋白 2 的强烈抑制作用及其对顺铂诱导的细胞毒性的减弱作用。
Chem Biol Interact. 2023 Jul 1;379:110504. doi: 10.1016/j.cbi.2023.110504. Epub 2023 Apr 20.
4
Influence of Oct1/Oct2-deficiency on cisplatin-induced changes in urinary N-acetyl-beta-D-glucosaminidase.Oct1/Oct2 缺失对顺铂诱导的尿 N-乙酰-β-D-氨基葡萄糖苷酶变化的影响。
Clin Cancer Res. 2010 Aug 15;16(16):4198-206. doi: 10.1158/1078-0432.CCR-10-0949. Epub 2010 Jul 2.
5
Clonidine ameliorates cisplatin-induced nephrotoxicity: impact on OCT2 and p38 MAPK pathway.可乐定改善顺铂诱导的肾毒性：对 OCT2 和 p38MAPK 通路的影响。
J Pharm Pharmacol. 2022 Aug 19;74(8):1180-1192. doi: 10.1093/jpp/rgac039.
6
Protective effect of concomitant administration of imatinib on cisplatin-induced nephrotoxicity focusing on renal organic cation transporter OCT2.伊马替尼联合给药对顺铂诱导的肾毒性的保护作用：聚焦于肾脏有机阳离子转运体OCT2
Biochem Pharmacol. 2009 Nov 1;78(9):1263-71. doi: 10.1016/j.bcp.2009.06.014. Epub 2009 Jun 18.
7
Ondansetron can enhance cisplatin-induced nephrotoxicity via inhibition of multiple toxin and extrusion proteins (MATEs).昂丹司琼可通过抑制多种毒素和外排蛋白（MATEs）增强顺铂诱导的肾毒性。
Toxicol Appl Pharmacol. 2013 Nov 15;273(1):100-9. doi: 10.1016/j.taap.2013.08.024. Epub 2013 Aug 31.
8
Membrane transporters as mediators of cisplatin side-effects.膜转运蛋白作为顺铂副作用的介导者。
Anticancer Res. 2014 Jan;34(1):547-50.
9
Wedelolactone protects against cisplatin-induced nephrotoxicity in mice via inhibition of organic cation transporter 2.韦地洛酮通过抑制有机阳离子转运体 2 保护顺铂诱导的小鼠肾毒性。
Hum Exp Toxicol. 2021 Dec;40(12_suppl):S447-S459. doi: 10.1177/09603271211047915. Epub 2021 Sep 30.
10
Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin.药效动力学模型评估 OCT2 抑制剂西咪替丁对顺铂抗癌作用的影响。
Cells. 2022 Dec 23;12(1):57. doi: 10.3390/cells12010057.
引用本文的文献
1
Targeting DNA Damage Response and Repair to Enhance Therapeutic Index in Cisplatin-Based Cancer Treatment.针对 DNA 损伤反应和修复以提高顺铂类癌症治疗的治疗指数。
Int J Mol Sci. 2021 Jul 30;22(15):8199. doi: 10.3390/ijms22158199.
2
The Role of Nucleotide Excision Repair in Cisplatin-Induced Peripheral Neuropathy: Mechanism, Prevention, and Treatment.核苷酸切除修复在顺铂诱导的周围神经病中的作用：机制、预防和治疗。
Int J Mol Sci. 2021 Feb 17;22(4):1975. doi: 10.3390/ijms22041975.
本文引用的文献
1
Cisplatin-Induced Nephrotoxicity; Protective Supplements and Gender Differences.顺铂诱导的肾毒性；保护性补充剂与性别差异。
Asian Pac J Cancer Prev. 2017 Feb 1;18(2):295-314. doi: 10.22034/APJCP.2017.18.2.295.
2
Organic Cation Transporter 2 (OCT2/SLC22A2) Gene Variation in the South African Bantu-Speaking Population and Functional Promoter Variants.南非班图语系人群中有机阳离子转运体2（OCT2/SLC22A2）基因变异及功能性启动子变体
OMICS. 2017 Mar;21(3):169-176. doi: 10.1089/omi.2016.0165. Epub 2017 Feb 16.
3
Dual function of OCT2 and MATE1 in cisplatin induced nephrotoxicity.OCT2和MATE1在顺铂诱导的肾毒性中的双重作用。
Pharmacol Res. 2017 May;119:493. doi: 10.1016/j.phrs.2016.11.023. Epub 2016 Nov 23.
4
Sex and age differences related to renal OCT2 gene expression in cisplatin-induced nephrotoxicity.
Iran J Kidney Dis. 2015 Jul;9(4):335-6.
5
Gender difference in Cisplatin-induced nephrotoxicity in a rat model.
Nephrourol Mon. 2015 Feb 19;7(2):e23595. doi: 10.5812/numonthly.23595. eCollection 2015 Mar.
6
Glutamine protects against cisplatin-induced nephrotoxicity by decreasing cisplatin accumulation.谷氨酰胺通过减少顺铂蓄积来预防顺铂诱导的肾毒性。
J Pharmacol Sci. 2015 Jan;127(1):117-26. doi: 10.1016/j.jphs.2014.11.009. Epub 2014 Dec 4.
7
Regulation of renal organic anion and cation transporters by thymoquinone in cisplatin induced kidney injury.姜黄素对顺铂诱导肾损伤中有机阴离子和阳离子转运体的调节作用。
Food Chem Toxicol. 2012 May;50(5):1675-9. doi: 10.1016/j.fct.2012.02.082. Epub 2012 Mar 3.
8
Regulatory role of testosterone in organic cation transport: in vivo and in vitro studies.
Biol Pharm Bull. 2009 Jun;32(6):982-7. doi: 10.1248/bpb.32.982.
Zotero 插件