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神经生理学方法在颈髓损伤上肢功能重建中的应用

A neurophysiological approach to nerve transfer to restore upper limb function in cervical spinal cord injury.

机构信息

Departments of 1 Neurosciences and.

Neurosurgery, University of California San Diego School of Medicine, La Jolla, California.

出版信息

Neurosurg Focus. 2017 Jul;43(1):E6. doi: 10.3171/2017.5.FOCUS17245.

Abstract

A successful nerve transfer surgery can provide a wealth of benefits to a patient with cervical spinal cord injury. The process of surgical decision making ideally uses all pertinent information to produce the best functional outcome. Reliance on clinical examination and imaging studies alone can miss valuable information on the state of spinal cord health. In this regard, neurophysiological evaluation has the potential to effectively gauge the neurological status of even select pools of anterior horn cells and their axons to small nerve branches in question to determine the potential efficacy of their use in a transfer. If available preoperatively, knowledge gained from such an evaluation could significantly alter the reconstructive surgical plan and avoid poor results. The authors describe their institution's approach to the assessment of patients with cervical spinal cord injury who are being considered for nerve transfer surgery in both the acute and chronic setting and broadly review the neurophysiological techniques used.

摘要

成功的神经转移手术可以为颈脊髓损伤患者带来诸多益处。手术决策过程理想情况下会利用所有相关信息来获得最佳的功能结果。仅依赖临床检查和影像学研究可能会遗漏有关脊髓健康状况的有价值信息。在这方面,神经生理学评估有可能有效地评估甚至是特定的前角细胞池及其轴突以及所涉及的小神经分支的神经状态,以确定其在转移中的使用效果。如果在术前获得这些信息,那么从评估中获得的知识可能会显著改变重建手术计划,并避免不良结果。作者描述了他们机构在急性和慢性环境下评估考虑进行神经转移手术的颈脊髓损伤患者的方法,并广泛回顾了所使用的神经生理学技术。

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