Parghane Rahul Vithalrao, Sood Ashwani, Vaiphei Kim, Aggarwal Ashutosh Nath, Mittal Bhagwant Rai
Department of Nuclear Medicine, PGIMER, Chandigarh, India.
Department of Histopathology, PGIMER, Chandigarh, India.
World J Nucl Med. 2017 Jul-Sep;16(3):240-242. doi: 10.4103/1450-1147.207280.
Tracheal metastases from renal cell carcinoma (RCC) are extremely rare. Most common primary malignancy metastasizing to this unusual location usually comes from lung region while it is rare to have tracheal metastases from nonpulmonary malignancies such as breast, thyroid, colorectal carcinoma, and melanoma. The lesions detected on fluorine-18 fluorodeoxyglucose (F-18 FDG) positron emission tomography/computed tomography (PET/CT) scan, especially in the head and neck region, soft tissue, and muscular compartment during follow-up of RCC patients raise the possibility of metastatic lesions in these regions, though rarely encountered. F-18 FDG PET/CT proved to be a valuable noninvasive imaging tool in detecting the very unusual distant metastases and multisystem involvement many years after nephrectomy in RCC in a single session in the present case.
肾细胞癌(RCC)的气管转移极为罕见。转移至这一不寻常部位的最常见原发性恶性肿瘤通常来自肺部区域,而非肺部恶性肿瘤(如乳腺癌、甲状腺癌、结直肠癌和黑色素瘤)发生气管转移则较为罕见。在RCC患者随访期间,氟-18氟脱氧葡萄糖(F-18 FDG)正电子发射断层扫描/计算机断层扫描(PET/CT)上检测到的病变,尤其是在头颈部区域、软组织和肌肉间隙,虽很少见,但增加了这些区域发生转移病变的可能性。在本病例中,F-18 FDG PET/CT被证明是一种有价值的非侵入性成像工具,可在肾切除术后多年的单次检查中检测到RCC非常罕见的远处转移和多系统受累情况。