Azam Faisal, Abubakerr Muneer, Gollins Simon
Department of Oncology, North Wales Cancer Treatment Centre, Glan Clwyd Hospital, Bodelwyddan, Rhyl, UK.
J Med Case Rep. 2008 Jul 25;2:249. doi: 10.1186/1752-1947-2-249.
Primary tumour of the kidney metastasizing to the tongue is very unusual and only anecdotal cases have been reported. An exhaustive literature review covering the period from 1911 onwards disclosed 28 cases. Out of those, only 3 cases presented initially with tongue metastases before the diagnosis of primary renal cell carcinoma.The prognosis for patients with lingual metastasis of renal cell carcinoma is poor. Treatment of tongue metastasis is usually palliative and aims to provide patient comfort by means of pain relief and prevention of bleeding and infection. Surgical excision is recommended as the primary treatment with emphasis on preservation of tongue structure and function.
We report a case of tongue metastasis as an initial presentation of renal cell carcinoma in a 78-year-old man. Initially thought to be primary tongue cancer but on review of his histopathology again, it was diagnosed to be a rare metastasis from kidney cancer.
Tongue metastasis from renal cell carcinoma is rare and its diagnosis is a challenge. The prognosis of patients with tongue metastasis is poor. Similar to the primary tumours of the tongue, metastatic lesions may be ulcerated or polypoid. Since the tongue is a rare metastatic site, when a lesion is detected, a thorough evaluation to distinguish between metastasis and primary cancer should be made as the management and prognosis vary.
原发性肾肿瘤转移至舌部非常罕见，仅有零星病例报道。对1911年以来的文献进行全面回顾后发现了28例病例。其中，只有3例在原发性肾细胞癌诊断之前最初就出现了舌部转移。肾细胞癌舌部转移患者的预后较差。舌部转移的治疗通常是姑息性的，旨在通过缓解疼痛、预防出血和感染来提高患者舒适度。建议手术切除作为主要治疗方法，重点是保留舌部结构和功能。
我们报告一例78岁男性患者，以舌部转移作为肾细胞癌的首发表现。最初被认为是原发性舌癌，但再次复查其组织病理学后，诊断为罕见的肾癌转移。
肾细胞癌舌部转移罕见，其诊断具有挑战性。舌部转移患者的预后较差。与原发性舌部肿瘤相似，转移病灶可能为溃疡型或息肉样。由于舌部是罕见的转移部位，当检测到病变时，应进行全面评估以区分转移和原发性癌症，因为治疗方法和预后有所不同。
