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尼日利亚埃邦伊州奥尼查地方政府区乌卡武社区感染儿童尿液参数的变异性

VARIABILITY OF URINE PARAMETERS IN CHILDREN INFECTED WITH IN UKAWU COMMUNITY, ONICHA LOCAL GOVERNMENT AREA, EBONYI STATE, NIGERIA.

作者信息

Elom Juliana Eze, Odikamnoro Oliver O, Nnachi Agwu Ulu, Ikeh Ifeanyi, Nkwuda John O

机构信息

Department of Applied Biology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria.

Department of Immunology, Faculty of Medicine, Nnamdi Azikiwe University, Awka, Nigeria.

出版信息

Afr J Infect Dis. 2017 Jun 8;11(2):10-16. doi: 10.21010/ajid.v11i2.2. eCollection 2017.

Abstract

BACKGROUND

Schistosomiasis, a chronic, debilitating and neglected tropical and sub-tropical water-borne ailment, is highly endemic in Nigeria, especially among primary school children in rural communities. The study on the variability of urine parameters in children infected with in Ukawu community, Onicha Local Government Area of Ebonyi State, was undertaken.

MATERIALS AND METHODS

Urine samples were aseptically collected from 400 primary school children in the community and analysed using chemical reagent strips and sedimentation techniques.

RESULTS

The study revealed an overall prevalence of 27% as 108 pupils out of 400 were infected with . in the area. Proteinuria, haematuria and leucocyturia were observed to occur in 67.0%, 79.0% and 74.9% respectively. Males had higher infections and higher occurrences of proteinuria, haematuria and leucocyturia (72.5%, 88.2% and 82.4% respectively). There was no significant difference with respect to sex (P<0.05). Children within ages 12-15 years had the highest prevalence of . (35.5%) while those within the ages of 4-7 had the least prevalence (11.4%). The difference in the rate of infection between the different age groups was significant, statistically (P>0.05). Children within ages 12-15 had the highest occurrence of proteinuria, haematuria and leucocyturia while children within ages 4-7 had the least occurrence of the three urine parameters. All the pupils excreting above 40 egg/10ml of urine had proteinuria, haematuria and leucocyturia.

CONCLUSION

The study revealed that the community studied is endemic with infections and the level of the urine parameters increased with the intensity of infection. Prompt case detection and treatment, good personal hygiene, eradication of snail hosts, public enlightenment and proper waste disposal are hereby recommended.

摘要

背景

血吸虫病是一种慢性、使人衰弱且被忽视的热带和亚热带水源性疾病,在尼日利亚高度流行,尤其是在农村社区的小学生中。本研究针对埃邦伊州奥尼查地方政府区乌卡武社区感染[此处原文缺失相关寄生虫名称]的儿童尿液参数变异性展开。

材料与方法

从该社区400名小学生中无菌采集尿液样本,并用化学试剂条和沉淀技术进行分析。

结果

研究显示总体感染率为27%,400名学生中有108人感染[此处原文缺失相关寄生虫名称]。该地区蛋白尿、血尿和白细胞尿的发生率分别为67.0%、79.0%和74.9%。男性感染率更高,蛋白尿、血尿和白细胞尿的发生率也更高(分别为72.5%、88.2%和82.4%)。性别方面无显著差异(P<0.05)。12至15岁的儿童感染[此处原文缺失相关寄生虫名称]的患病率最高(35.5%),而4至7岁的儿童患病率最低(11.4%)。不同年龄组之间的感染率差异具有统计学意义(P>0.05)。12至15岁的儿童蛋白尿、血尿和白细胞尿的发生率最高,而4至7岁的儿童这三项尿液参数的发生率最低。所有每10毫升尿液中排出虫卵超过40个的学生都有蛋白尿、血尿和白细胞尿。

结论

研究表明,所研究的社区存在[此处原文缺失相关寄生虫名称]感染流行情况,尿液参数水平随感染强度增加而升高。特此建议及时进行病例检测和治疗、保持良好个人卫生、消灭钉螺宿主、开展公众宣传以及妥善处理废物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/410b/5476808/ff390f220e0b/AJID-11-10-g001.jpg

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