Badertscher Léonie, Damak Hassen, Mercier Ludivine, Décosterd Dumeng
Service de médecine interne, Hôpital du Jura, Site de Delémont, 2800 Delémont.
Service des urgences et de sauvetage, Hôpital du Jura, Site de Delémont, 2800 Delémont.
Rev Med Suisse. 2016 Aug 10;12(526):1321-1325.
Despite major advances in prevention and treatment, febrile neutropenia remains one of the most concerning complications of cancer chemotherapy. Its prognosis depends directly on the quality of the initial management in the emergency department (ED). An initial assessment of circulatory and respiratory function, with vigorous resuscitation where necessary, should be followed by careful examination for potential source of infection. A broad-spectrum empirical antibacterial therapy should be given in a timespan < 1 hour. Multinational Association for Supportive Care in Cancer (MASCC) criteria were developed to help physicians make decisions about the site of care and overall management of these patients.
尽管在预防和治疗方面取得了重大进展，但发热性中性粒细胞减少症仍然是癌症化疗最令人担忧的并发症之一。其预后直接取决于急诊科（ED）初始管理的质量。首先应对循环和呼吸功能进行初步评估，必要时进行积极复苏，随后仔细检查潜在的感染源。应在<1小时内给予广谱经验性抗菌治疗。制定了多国癌症支持治疗协会（MASCC）标准，以帮助医生对这些患者的治疗地点和整体管理做出决策。
