Mulogo Edgar Mugema, Nahabwe Christopher, Bagenda Fred, Batwala Vincent
Department of Community Health, Mbarara University of Science and Technology, PO Box 1410, Mbarara, Uganda.
Rwampara Health Sub-District, PO Box 1, Mbarara, Uganda.
Infect Dis Poverty. 2017 Jul 4;6(1):104. doi: 10.1186/s40249-017-0313-3.
Treatment completion among tuberculosis patients remains low across various regions of Uganda, despite implementation of directly observed treatment short course. This study evaluated the determinants of treatment completion in a rural health sub-district of south western Uganda.
In April 2012, health facility records were reviewed to identify tuberculosis patients who had been initiated on treatment between June 2008 and May 2011, in Rwampara Health Sub-District, south-western Uganda. Out of the 162 patients identified, 128 (79%) were traced and subsequently interviewed during a survey conducted in June 2012. Eleven (6.8%) of the 162 patients died, while 23 (14.2%) could not be traced. A review of records showed that 17 of those that could not be traced completed treatment while the other six did not have definitive records.
Treatment completion among the 128 patients interviewed was 89.8%. Pre-treatment counselling (aOR = 24.3, 95% CI: 1.4-26.6, P = 0.03), counselling at the time of submission of sputum during follow up (aOR = 6.8, 95% CI: 1.4-33.7, P = 0.02), and refill of drugs on the exact appointment date (aOR = 13.4, 95% CI: 1.9-93.0, P = 0.01), were independently associated with treatment completion.
The level of treatment completion was higher than the national average, with service- related determinants identified as being critical for ensuring treatment completion. These data provide further evidence for the need to provide ongoing counselling support to tuberculosis patients. Enhancing the opportunities for counselling of tuberculosis patients should therefore be rigorously promoted as an approach to increase treatment completion in rural settings.
尽管实施了直接观察短程治疗,但乌干达各地区结核病患者的治疗完成率仍然很低。本研究评估了乌干达西南部一个农村卫生次区域治疗完成的决定因素。
2012年4月,对卫生机构记录进行审查,以确定2008年6月至2011年5月期间在乌干达西南部鲁万帕拉卫生次区域开始治疗的结核病患者。在确定的162例患者中,128例(79%)被追踪到,并于2012年6月进行的一项调查中接受了访谈。162例患者中有11例(6.8%)死亡,23例(14.2%)无法追踪到。记录审查显示,无法追踪到的患者中有17例完成了治疗,而其他6例没有确切记录。
接受访谈的128例患者的治疗完成率为89.8%。治疗前咨询(调整后比值比[aOR]=24.3,95%置信区间[CI]:1.4-26.6,P=0.03)、随访期间提交痰液时的咨询(aOR=6.8,95%CI:1.4-33.7,P=0.02)以及在确切预约日期补充药物(aOR=13.4,95%CI:1.9-93.0,P=0.01)与治疗完成独立相关。
治疗完成水平高于全国平均水平,已确定与服务相关的决定因素对确保治疗完成至关重要。这些数据为持续向结核病患者提供咨询支持的必要性提供了进一步证据。因此,应大力推广增加结核病患者咨询机会的方法,以提高农村地区的治疗完成率。