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[马里Point G大学医院肾脏病与血液透析科慢性血液透析贫血患者的管理:病例研究]

[Management of chronic hemodialysis patients with anemia: case study conducted in the Department of Nephrology and Hemodialysis at the University Hospital Point G in Mali].

作者信息

Tounkara Alhadji Ahmadou, Coulibaly Abdoul Mahama Sériba, Coulibaly Nouhoun, Traoré Békaye, Maïga Mahamane Kalil

机构信息

Service de Néphrologie et d'Hémodialyse du CHU du Point G, Bamako, Mali.

Centre National d'Appui à la Lutte Contre la Maladie, Bamako, Mali.

出版信息

Pan Afr Med J. 2017 Mar 23;26:167. doi: 10.11604/pamj.2017.26.167.10861. eCollection 2017.

Abstract

INTRODUCTION

Anemia is a frequent complication of Chronic Kidney Disease CKD commonly found in chronic haemodialysis patients. Patients management is mainly based on erythropoietin administration and iron supplementation. This study aimed to evaluate the management of chronic hemodialysis patients with anemia in the Department of Nephrology and Hemodialysis at the University Hospital Point G in Mali.

METHODS

We conducted a cross-sectional study from 1 to 31 August 2016.

RESULTS

63 patients out of a total of 174 participants were selected, 34 men and 29 women with a sex-ratio of 1.17 in favor of men. The average age of patients was 48,79 years ±11.59, the average duration of hemodialysis treatment time was 3,77years±2.6. Hospitalization rate for anemia in our dialysis patients was 84,12%. 92.1% of patients required blood transfusion, with an annual average of 5,81 blood bags ±5.91. 87.3% of cases required iron supplementation. Mean ferritin concentration and TSC were 1245 ng/ml±629,52 and 46,16%±19.12 respectively. Occasional administration of EPO doses not exceeding the 4000IU was reported by 79.4% of patients. The main difficulty in using EPO was its cost (74.6%). HCV infection was found in 60.1% of patients who were assessed.

CONCLUSION

The management of chronic dialysis patients with anemia should be integrated into the framework of the national health policy.

摘要

引言

贫血是慢性肾脏病(CKD)常见的并发症,在慢性血液透析患者中很常见。患者的管理主要基于促红细胞生成素的使用和铁剂补充。本研究旨在评估马里Point G大学医院肾脏病与血液透析科慢性血液透析贫血患者的管理情况。

方法

我们于2016年8月1日至31日进行了一项横断面研究。

结果

在总共174名参与者中,选取了63名患者,其中34名男性和29名女性,性别比为1.17,男性占优。患者的平均年龄为48.79岁±11.59岁,血液透析治疗的平均时长为3.77年±2.6年。我们透析患者的贫血住院率为84.12%。92.1%的患者需要输血,年平均输血量为5.81袋±5.91袋。87.3%的病例需要补充铁剂。铁蛋白平均浓度和转铁蛋白饱和度分别为1245 ng/ml±629.52和46.16%±19.12。79.4%的患者报告偶尔使用不超过4000国际单位的促红细胞生成素剂量。使用促红细胞生成素的主要困难是其成本(74.6%)。在接受评估的患者中,60.1%发现感染丙型肝炎病毒。

结论

慢性透析贫血患者的管理应纳入国家卫生政策框架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5df6/5483341/32c19f85a04a/PAMJ-26-167-g001.jpg

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