[微小RNA在牙釉质发育中的表达及功能]
[Expression and function of microRNAs in enamel development].
作者信息
Yachuan Zhou, Xuedong Zhou, Liwei Zheng
机构信息
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
出版信息
Hua Xi Kou Qiang Yi Xue Za Zhi. 2017 Jun 1;35(3):328-333. doi: 10.7518/hxkq.2017.03.018.
microRNAs (miRNAs) are endogenous short, noncoding RNAs that can negatively regulate gene expression post-transcriptionally. miRNAs are involved in multiple developmental events in various tissues and organs, including dental enamel development. Any disruption during enamel development may result in inherited enamel malformations. This article reviews the expression and function of miRNAs in enamel development.
微小RNA（miRNA）是内源性短链非编码RNA，可在转录后对基因表达进行负调控。miRNA参与包括牙釉质发育在内的各种组织和器官的多个发育过程。牙釉质发育过程中的任何干扰都可能导致遗传性牙釉质畸形。本文综述了miRNA在牙釉质发育中的表达及功能。
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