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The subcellular distribution of DL-[3H]2-amino-4-phosphonobutyrate binding sites in the rat brain.

作者信息

Butcher S P, Roberts P J, Collins J F

出版信息

Neurosci Lett. 1985 Nov 11;61(3):249-53. doi: 10.1016/0304-3940(85)90472-0.

Abstract

The subcellular distribution of DL-[3H]2-amino-4-phosphonobutyrate binding sites in rat brain was examined. Binding sites for this radioligand, which selectively labels a chloride/calcium-dependent subpopulation of glutamate binding sites, were highly concentrated in synaptic membrane fractions. This is wholly consistent with the proposed involvement of this site in physiological responses.

摘要

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