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巨大肝肿瘤的术前肝切除术——病例报告及文献综述

Ante-situm Liver Resection for Giant Hepatic Tumour - Case Report and Review of Literature.

作者信息

Braşoveanu Vladislav, Pautov Mihail, Ionescu Mihnea Ioan, Anghel Claudiu, Dudus Dan Ionut, Moothoor Manish, Ichim Florin, Gangone Eliza, Barbu Ion

出版信息

Chirurgia (Bucur). 2017 May-Jun;112(3):326-331. doi: 10.21614/chirurgia.112.3.326.

DOI:10.21614/chirurgia.112.3.326
PMID:28675368
Abstract

Ex-situ liver surgery refers to complex liver resections involving hepatic vascular exclusion and a warm ischemia time (WIT) of more than 90 minutes that allows liver resection and vascular reconstruction in patients with giant liver tumours with a difficult approach . Ante-situm liver resections, otherwise called "œex-situ in-vivo" resections is achieved through externalization of the liver outside of the abdominal cavity by clamping and sectioning of the efferent pedicles (suprahepatic veins) ("ex situ") without cutting the afferent vascular pedicle ("in vivo"), thus leaving the hepatic pedicle intact. We present a case report of a 36 yo male patient diagnosed by MRI scan with giant liver tumor in the left hemiliver. A left "ex-situ in-vivo" hepatectomy was performed by dissecting and ligating the left and middle hepatic veins, clamping and sectioning the right hepatic vein, Pringle maneuver, externalization of the liver followed by the tumor resection and right hepatic vein reimplantation. The short warm ischemia time (hepatic resection + liver reimplantation - 30 minutes) allowed us to perform the procedure without installing a veno-venous or porto-caval shunt otherwise used in all of ex-situ procedures described in the literature reviewed in this presentation. Ex-situ liver resection is a viable procedure for giant liver tumours in highly selected cases. It facilitates resection of large liver tumours that would be otherwise unresectable, extending the indications of surgical treatment.

摘要

体外肝手术是指涉及肝血管阻断且热缺血时间(WIT)超过90分钟的复杂肝切除术,该手术允许对手术入路困难的巨大肝肿瘤患者进行肝切除和血管重建。原位肝切除术,也称为“体内外”切除术,是通过夹闭和切断传出蒂(肝上静脉)将肝脏外置至腹腔外(“体外”),而不切断传入血管蒂(“体内”),从而保持肝蒂完整。我们报告一例36岁男性患者,经MRI扫描诊断为左半肝巨大肝肿瘤。通过解剖和结扎左、中肝静脉,夹闭和切断右肝静脉,行Pringle手法,将肝脏外置,随后切除肿瘤并重新植入右肝静脉,实施了左“体内外”肝切除术。短热缺血时间(肝切除+肝脏重新植入-30分钟)使我们能够在不安装文献中所述的所有体外手术中均使用的静脉-静脉或门静脉-腔静脉分流的情况下进行该手术。体外肝切除术对于高度选择的巨大肝肿瘤病例是一种可行的手术方法。它有助于切除否则无法切除的大肝肿瘤,扩大了手术治疗的适应证。

相似文献

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Ante-situm Liver Resection for Giant Hepatic Tumour - Case Report and Review of Literature.巨大肝肿瘤的术前肝切除术——病例报告及文献综述
Chirurgia (Bucur). 2017 May-Jun;112(3):326-331. doi: 10.21614/chirurgia.112.3.326.
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Modified ante situm liver resection without use of cold perfusion nor veno-venous bypass for treatment of hepatic lesions infiltrating the hepatocaval confluence.改良原位肝切除术,不使用冷灌注和静脉-静脉转流治疗浸润肝腔静脉汇合部的肝脏病变。
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Central hepatic resection under hypothermic total vascular exclusion using ante-situm techniques while maintaining liver blood supply.采用前位技术在低温全肝血流阻断下进行肝中央切除,同时维持肝脏血供。
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Selective hepatic vascular exclusion versus pringle maneuver in partial hepatectomy for liver hemangioma compressing or involving the major hepatic veins.肝血管瘤压迫或累及主要肝静脉的肝部分切除术中选择性肝血管阻断与第一肝门阻断的比较
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引用本文的文献

1
Anesthesia Management of Modified Ex Vivo Liver Resection and Autotransplantation.改良离体肝切除及自体肝移植的麻醉管理
Ann Transplant. 2018 Apr 27;23:274-284. doi: 10.12659/AOT.907796.
2
Modified ante situm liver resection without use of cold perfusion nor veno-venous bypass for treatment of hepatic lesions infiltrating the hepatocaval confluence.改良原位肝切除术,不使用冷灌注和静脉-静脉转流治疗浸润肝腔静脉汇合部的肝脏病变。
Langenbecks Arch Surg. 2018 May;403(3):379-386. doi: 10.1007/s00423-018-1658-1. Epub 2018 Feb 22.