Bocchialini Gabriele, Ferrari Luca, Rossini Manuela, Bozzola Anna, Burlini Dante
Maxillofacial Surgery Unit, Asst Spedali Civili, Brescia, Italy.
Maxillofacial Pediatric Surgery Unit, Ospedale dei Bambini-Asst., Spedali Civili, Brescia, Italy.
Int J Surg Case Rep. 2017;37:149-153. doi: 10.1016/j.ijscr.2017.06.018. Epub 2017 Jun 15.
Chronic nonbacterial osteomyelitis (CNO) or chronic recurrent multifocal osteomyelitis (CRMO), is a very rare condition of unknown aetiology. It is characterised by focal sterile inflammatory disease with prolonged, self-limiting and recurrent episodes.
We report the discovery of this very rare disease following a mandibular abscess in a 10-year-old female. We initially focus on the difference between the preoperative orthopantomography and the maxillofacial computed tomography and magnetic resonance images obtained, and then on the improvement of strategies for correct diagnosis and treatment of this disease.
Bone pain and localised swelling can occur in a single bone or can spread to soft tissue and adjacent bone; areas commonly affected by CMRO include the metaphyseal plates of the long bones, as well as the spine, clavicle and, rarely, the maxillofacial area. The clinical presentation of CMRO includes pain, functional impairment, and swelling, similar to our case.
We report a very rare case of this unifocal mandibular disease in a child who presented for an abscess and was then diagnosed and treated for CNO.
慢性非细菌性骨髓炎（CNO）或慢性复发性多灶性骨髓炎（CRMO）是一种病因不明的极为罕见的病症。其特征为局灶性无菌性炎症疾病，病程迁延、具有自限性且反复发作。
我们报告了一名10岁女性在下颌脓肿后发现这种极为罕见疾病的情况。我们首先关注术前曲面体层摄影与所获得的颌面计算机断层扫描及磁共振图像之间的差异，然后关注改善该疾病正确诊断和治疗策略的问题。
骨痛和局部肿胀可发生于单一骨骼，也可蔓延至软组织和相邻骨骼；CMRO常见受累部位包括长骨的干骺端，以及脊柱、锁骨，很少累及颌面区域。CMRO的临床表现包括疼痛、功能障碍和肿胀，与我们的病例相似。
我们报告了一名儿童单灶性下颌骨疾病的罕见病例，该患儿因脓肿就诊，随后被诊断为CNO并接受治疗。
