芳烃受体（AhR）参与多酚对苯并[a]芘诱导的氧化应激和肿瘤转化的抑制作用。 - Suppr

Involvement of aryl hydrocarbon receptor (AhR) in polyphenol inhibition of benzo[a]pyrene-induced oxidative stress and neoplastic transformation.

作者信息

Dvorak Zdenek

机构信息

Department of Cell Biology and Genetics, Faculty of Science, Palacky University Olomouc, Slechtitelu 27, 783 71 Olomouc, Czech Republic.

出版信息

Food Chem Toxicol. 2017 Sep;107(Pt A):523-525. doi: 10.1016/j.fct.2017.07.001. Epub 2017 Jul 1.

DOI:10.1016/j.fct.2017.07.001

PMID:28676325

Abstract

摘要

相似文献

Involvement of aryl hydrocarbon receptor (AhR) in polyphenol inhibition of benzo[a]pyrene-induced oxidative stress and neoplastic transformation.芳烃受体（AhR）参与多酚对苯并[a]芘诱导的氧化应激和肿瘤转化的抑制作用。

Food Chem Toxicol. 2017 Sep;107(Pt A):523-525. doi: 10.1016/j.fct.2017.07.001. Epub 2017 Jul 1.

Evidence against an involvement of aryl hydrocarbon receptor (AhR) in polyphenol inhibition of benzo[a]pyrene-induced oxidative stress and neoplastic transformation.关于芳烃受体（AhR）未参与多酚对苯并[a]芘诱导的氧化应激和肿瘤转化的抑制作用的证据。

Food Chem Toxicol. 2017 Sep;107(Pt A):526-527. doi: 10.1016/j.fct.2017.07.028. Epub 2017 Jul 13.

Exposure of human skin to benzo[a]pyrene: role of CYP1A1 and aryl hydrocarbon receptor in oxidative stress generation.人体皮肤接触苯并[a]芘：CYP1A1 和芳香烃受体在氧化应激产生中的作用。

Toxicology. 2010 May 27;271(3):83-6. doi: 10.1016/j.tox.2010.02.014. Epub 2010 Mar 20.

Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: an in vitro and in vivo study.砷诱导肺细胞和组织中CYP1A1表达及活性升高过程中氧化应激和芳烃受体激活的作用：一项体外和体内研究

Toxicol Sci. 2009 Feb;107(2):385-93. doi: 10.1093/toxsci/kfn239. Epub 2008 Nov 25.

Abundance of aryl hydrocarbon receptor potentiates benzo[a]pyrene-induced apoptosis in Hepa1c1c7 cells via CYP1A1 activation.芳烃受体的丰度通过激活CYP1A1增强苯并[a]芘诱导的Hepa1c1c7细胞凋亡。

Toxicology. 2007 Jun 3;235(1-2):62-72. doi: 10.1016/j.tox.2007.03.013. Epub 2007 Mar 15.

Genotoxic polycyclic aromatic hydrocarbon ortho-quinones generated by aldo-keto reductases induce CYP1A1 via nuclear translocation of the aryl hydrocarbon receptor.由醛酮还原酶生成的具有基因毒性的多环芳烃邻醌通过芳烃受体的核转位诱导CYP1A1。

Cancer Res. 2000 Feb 15;60(4):908-15.

Interaction of a functionalized complex of the flavonoid hesperetin with the AhR pathway and CYP1A1 expression: involvement in its protective effects against benzo[a]pyrene-induced oxidative stress in human skin.黄酮类化合物橙皮素的功能化复合物与 AhR 途径和 CYP1A1 表达的相互作用：在其对苯并[a]芘诱导的人体皮肤氧化应激的保护作用中的作用。

Cell Biol Toxicol. 2011 Oct;27(5):371-9. doi: 10.1007/s10565-011-9194-6. Epub 2011 Jul 1.

Benzo[a]pyrene, 3-methylcholanthrene and beta-naphthoflavone induce oxidative stress in hepatoma hepa 1c1c7 Cells by an AHR-dependent pathway.苯并[a]芘、3-甲基胆蒽和β-萘黄酮通过芳烃受体（AHR）依赖性途径在肝癌Hepa 1c1c7细胞中诱导氧化应激。

Free Radic Res. 2004 Nov;38(11):1191-200. doi: 10.1080/10715760400017319.

Benzo[g,h,i]perylene synergistically transactivates benzo[a]pyrene-induced CYP1A1 gene expression by aryl hydrocarbon receptor pathway.苯并[g,h,i]苝通过芳烃受体途径协同反式激活苯并[a]芘诱导的CYP1A1基因表达。

Toxicol Appl Pharmacol. 2001 Jan 1;170(1):63-8. doi: 10.1006/taap.2000.9082.

Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene.通过苯并[a]芘的CYP1亚型选择性代谢失活抑制芳烃受体反式激活和DNA加合物形成。

Toxicol Appl Pharmacol. 2008 Jul 15;230(2):135-43. doi: 10.1016/j.taap.2008.02.009. Epub 2008 Feb 21.

引用本文的文献

The Alkaloid Caulerpin Exhibits Potent and Selective Anti-Inflammatory Activity Through Interaction with the Glucocorticoid Receptor.生物碱刺参碱通过与糖皮质激素受体相互作用表现出强效且选择性的抗炎活性。

Mar Drugs. 2025 May 29;23(6):232. doi: 10.3390/md23060232.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Involvement of aryl hydrocarbon receptor (AhR) in polyphenol inhibition of benzo[a]pyrene-induced oxidative stress and neoplastic transformation.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

文献检索

文件翻译

深度研究

Suppr 超能文献

相似文献

引用本文的文献