Slane Laura C, Slane Josh A, Scheys Lennart
Institute for Orthopaedic Research and Training, KU Leuven, Oude Markt 13, 3000, Louvain, Belgium.
Institute for Orthopaedic Research and Training (IORT), KU Leuven, UZ Pellenberg, Weligerveld 1/Blok 1, 3212, Pellenberg, Belgium.
Arch Orthop Trauma Surg. 2017 Aug;137(8):1121-1128. doi: 10.1007/s00402-017-2740-9. Epub 2017 Jul 4.
Medial knee instability is a key clinical parameter for assessing ligament injury and arthroplasty success, but current methods for measuring stability are typically either qualitative or involve ionizing radiation. The purpose of this study was to perform a preliminary analysis of whether ultrasound (US) could be used as an alternate approach for quantifying medial instability by comparing an US method with an approach mimicking the current gold standard fluoroscopy method.
US data from the medial knee were collected, while cadaveric lower limbs (n = 8) were loaded in valgus (10 Nm). During post-processing, the US gap width was measured by identifying the medial edges of the femur and tibia and computing the gap width between these points. For comparison, mimicked fluoroscopy (mFluoro) images were created from specimen-specific bone models, developed from segmented CT scans, and from kinematic data collected during testing. Then, gap width was measured in the mFluoro images based on two different published approaches with gap width measured either at the most medial or at the most distal aspect of the femur.
Gap width increased significantly with loading (p < 0.001), and there were no significant differences between the US method (unloaded: 8.7 ± 2.4 mm, loaded: 10.7 ± 2.2 mm) and the mFluoro method that measured gap width at the medial femur. In terms of the change in gap width with load, no correlation with the change in abduction angle was observed, with no correlation between the various methods. Inter-rater reliability for the US method was high (0.899-0.952).
Ultrasound shows promise as a suitable alternative for quantifying medial instability without radiation exposure. However, the outstanding limitations of existing approaches and lack of true ground-truth data require that further validation work is necessary to better understand the clinical viability of an US approach for measuring medial knee gap width.
膝关节内侧不稳定是评估韧带损伤和关节置换术成功与否的关键临床参数,但目前测量稳定性的方法通常要么是定性的,要么涉及电离辐射。本研究的目的是通过将超声(US)方法与模拟当前金标准荧光透视法的方法进行比较,对超声是否可作为量化内侧不稳定的替代方法进行初步分析。
收集膝关节内侧的超声数据,同时对8具尸体下肢施加外翻负荷(10牛米)。在后期处理过程中,通过识别股骨和胫骨的内侧边缘并计算这些点之间的间隙宽度来测量超声间隙宽度。为了进行比较,从基于断层扫描分割得到的特定标本骨模型以及测试过程中收集的运动学数据创建模拟荧光透视(mFluoro)图像。然后,根据两种不同的已发表方法在mFluoro图像中测量间隙宽度,间隙宽度分别在股骨最内侧或最远端测量。
间隙宽度随负荷显著增加(p < 0.001),超声方法(未加载:8.7±2.4毫米,加载:10.7±2.2毫米)与在股骨内侧测量间隙宽度的mFluoro方法之间无显著差异。就间隙宽度随负荷的变化而言,未观察到与外展角度变化的相关性,各方法之间也无相关性。超声方法的评分者间可靠性较高(0.899 - 0.952)。
超声有望成为一种无需辐射暴露即可量化内侧不稳定的合适替代方法。然而,现有方法的显著局限性以及缺乏真实的地面真值数据要求进行进一步的验证工作,以更好地了解超声测量膝关节内侧间隙宽度方法的临床可行性。