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早泄:药物治疗与单独或联合团体心理治疗的对比

Premature ejaculation: Pharmacotherapy vs group psychotherapy alone or in combination.

作者信息

Pavone Carlo, Abbadessa Daniela, Gambino Giuseppa, Scaduto Giovanna, Vella Marco

机构信息

Section of Urology, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo.

出版信息

Arch Ital Urol Androl. 2017 Jun 30;89(2):114-119. doi: 10.4081/aiua.2017.2.114.

DOI:10.4081/aiua.2017.2.114
PMID:28679182
Abstract

OBJECTIVES

Premature Ejaculation (PE), the commonest sexual dysfunction in males, is generally treated with local anesthetic and SSRI (Dapoxetine). The aim of our study was investigate Group Psychotherapy as an alternative treatment for PE and compare the efficacy of pharmacological treatment and psychotherapy, either alone or in combination, in terms of response and improved Quality of Life (QoL). From a male outpatient population screened for PE, those who received a diagnosis of PE were proposed for the study, enrolled and divided into 3 groups (A, B and C). Each group was treated with Dapoxetine, Group Psychotherapy alone and Dapoxetine and Group Psychotherapy, respectively.

MATERIALS AND METHODS

Out of 1237 male outpatients, 353 received a diagnosis of Premature Ejaculation. Of them, 279 were enrolled in the study and randomized into 3 groups (A, B and C). Only 157 patients were evaluable. Before and after treatments all participants completed two questionnaires to evaluate PE status and anxiety and referred their IELT.

RESULTS

GROUP A: The mean post-treatment Premature Ejaculation Diagnostic Tool (PEDT) score decreased from 12.95 to 8.26, while the mean Intra-vaginal Ejaculation Latency Time (IELT) increased from 50.77 sec to 203 sec. (p < 0.05); GROUP B: Reduction in the mean PEDT from 13.44 to 5.11 and an increased IELT from 48.33 to 431.11 sec (p < 0.001); GROUP C: The mean post-treatment PEDT score decreased from 12.29 to 5.57, while the mean IELT increased from 46.86 to 412.14 sec (p < 0.001). All groups recorded an improvement in anxiety.

CONCLUSIONS

According to our results Group Psychotherapy is an alternative method of treatment for PE. Group Psychotherapy plays a significant role in the treatment of PE, determining a better improvement of symptoms than Dapoxetine alone even if not statistically significant.

摘要

目的

早泄(PE)是男性最常见的性功能障碍,通常采用局部麻醉剂和5-羟色胺再摄取抑制剂(达泊西汀)进行治疗。我们研究的目的是调查团体心理治疗作为早泄的一种替代治疗方法,并比较药物治疗和心理治疗单独或联合使用在反应和改善生活质量(QoL)方面的疗效。从筛查早泄的男性门诊患者中,那些被诊断为早泄的患者被纳入研究,登记并分为3组(A、B和C)。每组分别接受达泊西汀、单独的团体心理治疗以及达泊西汀与团体心理治疗。

材料与方法

在1237名男性门诊患者中,353人被诊断为早泄。其中,279人被纳入研究并随机分为3组(A、B和C)。只有157名患者可进行评估。在治疗前后,所有参与者都完成了两份问卷以评估早泄状况和焦虑情况,并报告了他们的阴道内射精潜伏期。

结果

A组:治疗后早泄诊断工具(PEDT)平均得分从12.95降至8.26,而阴道内射精潜伏期(IELT)平均从50.77秒增加到203秒。(p < 0.05);B组:PEDT平均得分从13.44降至5.11,IELT从48.33秒增加到431.11秒(p < 0.001);C组:治疗后PEDT平均得分从12.29降至5.57,而IELT平均从46.86秒增加到412.14秒(p < 0.001)。所有组的焦虑情况均有所改善。

结论

根据我们的结果,团体心理治疗是早泄的一种替代治疗方法。团体心理治疗在早泄治疗中发挥着重要作用,即使在统计学上不显著,但与单独使用达泊西汀相比,能更好地改善症状。

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