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Lipid-Lowering and Anti-Inflammatory Benefits of Statin Therapy: More Than Meets the Plaque.

作者信息

Taqueti Viviany R, Ridker Paul M

机构信息

From the Division of Cardiovascular Medicine, Cardiovascular Imaging Program (V.R.T., P.M.R.); Center for Cardiovascular Disease Prevention (P.M.R.); Division of Nuclear Medicine and Molecular Imaging (V.R.T.); Departments of Medicine and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

From the Division of Cardiovascular Medicine, Cardiovascular Imaging Program (V.R.T., P.M.R.); Center for Cardiovascular Disease Prevention (P.M.R.); Division of Nuclear Medicine and Molecular Imaging (V.R.T.); Departments of Medicine and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

出版信息

Circ Cardiovasc Imaging. 2017 Jul;10(7). doi: 10.1161/CIRCIMAGING.117.006676.

DOI:10.1161/CIRCIMAGING.117.006676
PMID:28679526
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5757307/
Abstract
摘要

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2
Excess Cardiovascular Risk in Women Relative to Men Referred for Coronary Angiography Is Associated With Severely Impaired Coronary Flow Reserve, Not Obstructive Disease.因冠状动脉造影而接受检查的女性相对于男性存在额外的心血管风险,这与严重受损的冠状动脉血流储备有关,而非阻塞性疾病。
Circulation. 2017 Feb 7;135(6):566-577. doi: 10.1161/CIRCULATIONAHA.116.023266. Epub 2016 Nov 14.
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Effect of Statin Treatment on Modifying Plaque Composition: A Double-Blind, Randomized Study.他汀类药物治疗对斑块成分的影响:一项双盲、随机研究。
J Am Coll Cardiol. 2016 Apr 19;67(15):1772-1783. doi: 10.1016/j.jacc.2016.02.014.
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Eur Heart J. 2016 Jun 7;37(22):1720-2. doi: 10.1093/eurheartj/ehw024. Epub 2016 Feb 22.
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Circ Res. 2016 Jan 8;118(1):145-56. doi: 10.1161/CIRCRESAHA.115.306656.
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Circulation. 2015 Sep 29;132(13):1224-33. doi: 10.1161/CIRCULATIONAHA.115.018381. Epub 2015 Sep 1.
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Increased microvascularization and vessel permeability associate with active inflammation in human atheromata.微血管生成增加和血管通透性增加与人类动脉粥样硬化中的活动性炎症相关。
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