Yoon Da-Le, Kim Yong-Gun, Cho Jin-Hyun, Lee Jae-Mok, Lee Sang-Kyu
Department of Periodontology, School of Dentistry, Kyungpook National University, Daegu, Korea.
Department of Prosthodontics, School of Dentistry, Kyungpook National University, Daegu, Korea.
J Adv Prosthodont. 2017 Jun;9(3):224-231. doi: 10.4047/jap.2017.9.3.224. Epub 2017 Jun 19.
This study was designed to evaluate the teeth and dental implants during dental maintenance therapy over 3 years in different conditions after periodontal and dental prosthetic treatment.
166 patients received maintenance therapy. 59 patients were treated with 2% minocycline-HCl ointment as local drug delivery (LDD) (L group) and 107 patients were treated without LDD (NL group). Clinical data was collected in maintenance period for evaluation. Patients were classified into groups depending on the application of LDD with maintenance therapy, the type of dental treatment before maintenance period (Pre-Tx), the frequency (F-MT), and regularity (R-MT) of maintenance therapy.
The numbers of lost teeth (N-teeth, =.003) and newly placed dental implants (N-implants, =.022) are significantly different according to Pre-Tx. F-MT among patients who received surgical dental treatment before maintenance period showed statistical differences in N-teeth (=.041), but not in N-implants (=.564). All of the patients in L group showed high F-MT (F-MT1). In NL group, there were no statistical differences in N-teeth or N-implants according to F-MT or R-MT. In F-MT1 group, application of LDD made N-teeth significantly different from both Pre-Tx groups while no significant difference could be found in N-implant. Independent t-test and one-way ANOVA were selected for statistical analysis.
The regular maintenance therapy and LDD can be effective for teeth during maintenance period. It is not only pharmacological efficacy in decreasing bacterial species that makes LDD a useful adjunct. Application of LDD also motivates patients to take adequate check-ups in the aspects of both frequency and regularity.
本研究旨在评估牙周和牙修复治疗后处于不同状况的患者在3年牙齿维护治疗期间的牙齿及牙种植体情况。
166例患者接受维护治疗。59例患者采用2%盐酸米诺环素软膏进行局部药物递送（LDD）治疗（L组），107例患者未进行LDD治疗（NL组）。在维护期收集临床数据进行评估。根据维护治疗中LDD的应用情况、维护期前的牙科治疗类型（治疗前）、维护治疗的频率（F-MT）和规律性（R-MT）对患者进行分组。
根据治疗前情况，失牙数量（N-牙齿，P =.003）和新植入牙种植体数量（N-种植体，P =.022）存在显著差异。维护期前接受牙科手术治疗的患者中，F-MT在N-牙齿方面存在统计学差异（P =.041），但在N-种植体方面无差异（P =.564）。L组所有患者均表现出高F-MT（F-MT1）。在NL组中，根据F-MT或R-MT，N-牙齿或N-种植体无统计学差异。在F-MT1组中，LDD的应用使N-牙齿与两个治疗前组均有显著差异，而N-种植体无显著差异。选择独立t检验和单因素方差分析进行统计分析。
定期维护治疗和LDD在维护期对牙齿可能有效。LDD不仅在减少细菌种类方面具有药理作用，使其成为一种有用的辅助手段。LDD的应用还促使患者在检查频率和规律性方面进行充分的检查。
