毛细胞型星形细胞瘤：一种罕见的表现为脑室内肿瘤的情况。

Pilocytic astrocytoma: A rare presentation as intraventricular tumor.

作者信息

Sattar Sidra, Akhunzada Naveed Z, Javed Gohar, Uddin Zeeshan, Khan Yasir A

机构信息

Community Health Sciences Department, Ziauddin University, Karachi, Pakistan.

Department of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.

出版信息

Surg Neurol Int. 2017 Jun 13;8:116. doi: 10.4103/sni.sni_468_16. eCollection 2017.

DOI:10.4103/sni.sni_468_16

PMID:28680735

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5482168/

Abstract

BACKGROUND

Pilocytic astrocytoma (PA) is the most prevalent central nervous system (CNS) tumor in pediatric population and accounts for an approximate of 5-6% of all gliomas. This neoplasm can occur at all levels of the neuraxis, with majority (67%) arising in the cerebellum and optic pathway. PAs are World Health Organization Grade I tumors and are the most benign of all astrocytomas characterized by an excellent prognosis. Other differentials include subependymal giant cell astrocytoma (SEGA), ependymoma, meningioma, and low-grade gliomas such as pilocytic or diffuse astrocytoma; calcification is more commonly regarded as a feature of benign or slow-growing tumors.

CASE DESCRIPTION

We present a case of a 17-year-old female presenting with an unusual cause of hydrocephalus, a rare case of a calcified pilocytic astrocytoma as an intraventricular tumor.

CONCLUSION

PA rarely presents as an intraventricular tumor and should be included in the differential diagnosis of a large mass with massive intratumoral calcification.

摘要

背景

毛细胞型星形细胞瘤（PA）是儿童人群中最常见的中枢神经系统（CNS）肿瘤，约占所有胶质瘤的5 - 6%。这种肿瘤可发生于神经轴的各个水平，大多数（67%）起源于小脑和视路。PA是世界卫生组织一级肿瘤，是所有星形细胞瘤中最良性的，预后极佳。其他鉴别诊断包括室管膜下巨细胞星形细胞瘤（SEGA）、室管膜瘤、脑膜瘤以及低级别胶质瘤，如毛细胞型或弥漫性星形细胞瘤；钙化更常被视为良性或生长缓慢肿瘤的特征。