抗精神病药恶性综合征

Neuroleptic malignant syndrome.

作者信息

Keltner N L, McIntyre C W

出版信息

J Neurosurg Nurs. 1985 Dec;17(6):362-6. doi: 10.1097/01376517-198512000-00006.

DOI:10.1097/01376517-198512000-00006

Abstract

The neuroleptic malignant syndrome (NMS) is a potentially fatal complication of antipsychotic drugs. It is characterized by severe muscular rigidity, hyperthermia, and autonomic disturbances. Neuroleptic malignant syndrome is easily confused with other health problems; distinctions between it and malignant hyperthermia, heatstroke, and lethal catatonia are made. The relevant literature is reviewed; a case history is presented; and implications for nursing care (e.g., early detection) are discussed.

摘要

抗精神病药物恶性综合征（NMS）是抗精神病药物潜在的致命并发症。其特征为严重的肌肉强直、高热和自主神经功能紊乱。抗精神病药物恶性综合征很容易与其他健康问题相混淆；需明确它与恶性高热、中暑及致死性紧张症之间的区别。本文回顾了相关文献；呈现了一个病例史；并讨论了对护理的启示（如早期发现）。