Ramirez Christina, Donnellan Nicole
Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Curr Opin Obstet Gynecol. 2017 Aug;29(4):225-230. doi: 10.1097/GCO.0000000000000379.
Chronic pelvic pain and dysmenorrhea are common conditions affecting reproductive-age women. Surgical pelvic denervation procedures may be a treatment option for women with midline dysmenorrhea, in which medical management is declined by the patient, ineffective at managing symptoms, or medically contraindicated. This review describes the surgical techniques and complications associated with pelvic denervation procedures as well as the current evidence for these procedures in women with primary dysmenorrhea and dysmenorrhea secondary to endometriosis.
Presacral neurectomy is the preferred pelvic denervation procedure in patients with primary dysmenorrhea and midline chronic pelvic pain associated with endometriosis. In patients with endometriosis presacral neurectomy is a useful adjunct to excision or ablation of all endometrial lesions to improve postoperative pain relief. There is no additional patient benefit of performing combined presacral neurectomy and uterine nerve ablation procedures.
Pelvic denervation procedures can be performed safely and quickly with a low risk of complication if the surgeon is knowledgeable and skilled in operating in the presacral space. Patients should be adequately counseled on expected success rates and potential complications associated with pelvic denervation procedures.
慢性盆腔疼痛和痛经是影响育龄期女性的常见病症。对于中线痛经患者,若患者拒绝药物治疗、药物治疗症状控制无效或存在药物治疗禁忌证,手术性盆腔去神经支配术可能是一种治疗选择。本综述描述了盆腔去神经支配术相关的手术技术和并发症,以及这些手术在原发性痛经和子宫内膜异位症继发性痛经女性中的现有证据。
对于原发性痛经和与子宫内膜异位症相关的中线慢性盆腔疼痛患者,骶前神经切除术是首选的盆腔去神经支配术。对于子宫内膜异位症患者,骶前神经切除术是切除或消融所有子宫内膜病变的有用辅助手段,可改善术后疼痛缓解情况。联合进行骶前神经切除术和子宫神经切除术并无额外的患者获益。
如果外科医生在骶前间隙手术方面知识渊博且技术熟练,盆腔去神经支配术可以安全、快速地进行,并发症风险较低。应就盆腔去神经支配术的预期成功率和潜在并发症对患者进行充分的咨询。